It has become widely accepted that humans use contextual information to infer the meaning
of ambiguous acoustic signals. In speech, for example, high-level semantic, syntactic, or …

The inferior colliculus (IC) is a critical computational hub in the central auditory pathway.
From its position in the midbrain, the IC receives nearly all the ascending output from the …

Neurons in the developing auditory system exhibit spontaneous bursts of activity before
hearing onset. How this intrinsically generated activity influences development remains …

Abstract Layer 5 (L5) cortical projection neurons innervate far-ranging brain areas to
coordinate integrative sensory processing and adaptive behaviors. Here, we characterize a …

Neurons that process sensory information exhibit bursts of electrical activity during
development, providing early training to circuits that will later encode similar features of the …

The cerebral cortex and cerebellum both play important roles in sensorimotor processing,
however, precise connections between these major brain structures remain elusive. Using …

Integration of information across the senses is critical for perception and is a common
property of neurons in the cerebral cortex, where it is thought to arise primarily from …

Neural adaptation enables sensory information to be represented optimally in the brain
despite large fluctuations over time in the statistics of the environment. Auditory contrast gain …

The extensive feedback from the auditory cortex (AC) to the inferior colliculus (IC) supports
critical aspects of auditory behavior but has not been extensively characterized. Previous …

Topographic representation of the receptor surface is a fundamental feature of sensory
cortical organization. This is imparted by the thalamus, which relays information from the …