Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …

Adenosine deaminase acting on RNA (ADAR) catalyzes the posttranscriptional conversion
of adenosine to inosine in double‐stranded RNA (dsRNA), which can lead to the creation of …

Stem-Cell Aging and Pathways to Precancer Evolution | New England Journal of Medicine Skip
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Summary Adenosine-to-inosine (A-to-I) RNA editing is a widespread post-transcriptional
mechanism, but its genomic landscape and clinical relevance in cancer have not been …

Abstract Adenosine-to-inosine (A-to-I) RNA editing, which is catalyzed by a family of
adenosine deaminase acting on RNA (ADAR) enzymes, is important in the epitranscriptomic …

Chronic myeloid leukaemia (CML) is a myeloproliferative disorder arising in the
haemopoietic stem cell (HSC) compartment. This disease is characterised by a reciprocal t …

Abstract A-to-I RNA editing is a post-transcriptional modification that converts adenosines to
inosines in both coding and noncoding RNA transcripts. It is catalyzed by ADAR (adenosine …

Every year, more than 8000 new cases of chronic myeloid leukemia (CML) are diagnosed in
the United States. 1 BCR-ABL1, a fusion protein kinase derived from a reciprocal …

Post-transcriptional adenosine-to-inosine RNA editing mediated by adenosine deaminase
acting on RNA1 (ADAR1) promotes cancer progression and therapeutic resistance …

With the goal to remove the roots of cancer, eliminate metastatic seeds, and overcome
therapy resistance, the 2014 inaugural International Cancer Stem Cell (CSC) Conference at …