[HTML][HTML] Stem cell programs in cancer initiation, progression, and therapy resistance
Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …
The role of RNA editing enzyme ADAR1 in human disease
B Song, Y Shiromoto, M Minakuchi… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Adenosine deaminase acting on RNA (ADAR) catalyzes the posttranscriptional conversion
of adenosine to inosine in double‐stranded RNA (dsRNA), which can lead to the creation of …
of adenosine to inosine in double‐stranded RNA (dsRNA), which can lead to the creation of …
Stem-cell aging and pathways to precancer evolution
CHM Jamieson, IL Weissman - New England Journal of Medicine, 2023 - Mass Medical Soc
Stem-Cell Aging and Pathways to Precancer Evolution | New England Journal of Medicine Skip
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …
[HTML][HTML] The genomic landscape and clinical relevance of A-to-I RNA editing in human cancers
Summary Adenosine-to-inosine (A-to-I) RNA editing is a widespread post-transcriptional
mechanism, but its genomic landscape and clinical relevance in cancer have not been …
mechanism, but its genomic landscape and clinical relevance in cancer have not been …
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation
Abstract Adenosine-to-inosine (A-to-I) RNA editing, which is catalyzed by a family of
adenosine deaminase acting on RNA (ADAR) enzymes, is important in the epitranscriptomic …
adenosine deaminase acting on RNA (ADAR) enzymes, is important in the epitranscriptomic …
Natural course and biology of CML
B Chereda, JV Melo - Annals of hematology, 2015 - Springer
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder arising in the
haemopoietic stem cell (HSC) compartment. This disease is characterised by a reciprocal t …
haemopoietic stem cell (HSC) compartment. This disease is characterised by a reciprocal t …
[HTML][HTML] Adenosine-to-inosine RNA editing and human disease
W Slotkin, K Nishikura - Genome medicine, 2013 - Springer
Abstract A-to-I RNA editing is a post-transcriptional modification that converts adenosines to
inosines in both coding and noncoding RNA transcripts. It is catalyzed by ADAR (adenosine …
inosines in both coding and noncoding RNA transcripts. It is catalyzed by ADAR (adenosine …
Mechanisms of resistance to ABL kinase inhibition in chronic myeloid leukemia and the development of next generation ABL kinase inhibitors
AB Patel, T O'Hare… - Hematology/Oncology …, 2017 - hemonc.theclinics.com
Every year, more than 8000 new cases of chronic myeloid leukemia (CML) are diagnosed in
the United States. 1 BCR-ABL1, a fusion protein kinase derived from a reciprocal …
the United States. 1 BCR-ABL1, a fusion protein kinase derived from a reciprocal …
[HTML][HTML] ADAR1 activation drives leukemia stem cell self-renewal by impairing Let-7 biogenesis
MA Zipeto, A Sadarangani, NPD Santos, L Balaian… - Cell stem cell, 2016 - cell.com
Post-transcriptional adenosine-to-inosine RNA editing mediated by adenosine deaminase
acting on RNA1 (ADAR1) promotes cancer progression and therapeutic resistance …
acting on RNA1 (ADAR1) promotes cancer progression and therapeutic resistance …
Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance
V Adorno-Cruz, G Kibria, X Liu, M Doherty, DJ Junk… - Cancer research, 2015 - AACR
With the goal to remove the roots of cancer, eliminate metastatic seeds, and overcome
therapy resistance, the 2014 inaugural International Cancer Stem Cell (CSC) Conference at …
therapy resistance, the 2014 inaugural International Cancer Stem Cell (CSC) Conference at …