The long-term health outcomes, pathophysiological mechanisms and multidisciplinary management of long COVID

J Li, Y Zhou, J Ma, Q Zhang, J Shao, S Liang… - … and Targeted Therapy, 2023 - nature.com
There have been hundreds of millions of cases of coronavirus disease 2019 (COVID-19),
which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With …

Long-term health outcomes associated with hydration status

NI Dmitrieva, M Boehm, PH Yancey… - Nature Reviews …, 2024 - nature.com
Body water balance is determined by fundamental homeostatic mechanisms that maintain
stable volume, osmolality and the composition of extracellular and intracellular fluids. Water …

Hypothesis: inflammatory acid-base disruption underpins Long Covid

V van der Togt, JS Rossman - Frontiers in Immunology, 2023 - frontiersin.org
The mechanism of Long Covid (Post-Acute Sequelae of COVID-19; PASC) is currently
unknown, with no validated diagnostics or therapeutics. SARS-CoV-2 can cause …

Health-related quality of life after surviving intensive care for COVID-19: a prospective multicenter cohort study

P Halvorsen, M Hultström, J Hästbacka, IM Larsson… - Scientific Reports, 2023 - nature.com
In survivors of severe coronavirus disease 2019 (COVID-19) incomplete mental and
physical recovery may considerably impact daily activities and health-related quality of life …

Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients

A Barrueta Tenhunen, G Butler-Laporte… - Physiological …, 2024 - journals.physiology.org
Hypertonic dehydration is associated with muscle wasting and synthesis of organic
osmolytes. We recently showed a metabolic shift to amino acid production and urea cycle …

Vasopressin, protein metabolism, and water conservation

JS Carty, JA Watts, JP Arroyo - Current Opinion in Nephrology …, 2024 - journals.lww.com
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Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients

AB Tenhunen, G Butler-Laporte… - Physiological …, 2024 - journals.physiology.org
Hypertonic dehydration is associated with muscle wasting and synthesis of organic
osmolytes. We recently showed a metabolic shift to amino acid production and urea cycle …

The Role of Electronic Health Records to Identify Risk Factors for Developing Long COVID: A Scoping Review

E Santos, A Fernandes, M Graça, NP Rocha - World Conference on …, 2024 - Springer
Abstract Coronavirus disease 2019 (COVID-19) was considered a global pandemic from
December 2019 to May 2023. A subset of COVID-19 patients develops long-lasting …

Adaptations of microbial genomes to human body chemistry

JM Dick - bioRxiv, 2023 - biorxiv.org
Water and oxygen availability vary in normal physiology and disease, so evolutionary
adjustments of protein sequences to optimally use these chemical resources would …

[HTML][HTML] Two dimensions of chemical variation of the human microbiome across body sites and in COVID-19 patients

JM Dick - 2023 - europepmc.org
A better understanding of dysbiosis is a major goal of human microbiome studies, but more
knowledge about chemical effects on microbial communities is needed. Oxidation-reduction …