Reservoirs and transmission routes of leprosy; A systematic review

T Ploemacher, WR Faber, H Menke… - PLoS neglected …, 2020 - journals.plos.org
Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the
more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy …

Infectious disease risk across the growing human-non human primate interface: a review of the evidence

CA Devaux, O Mediannikov, H Medkour… - Frontiers in public …, 2019 - frontiersin.org
Most of the human pandemics reported to date can be classified as zoonoses. Among these,
there is a long history of infectious diseases that have spread from non-human primates …

[HTML][HTML] Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe

VJ Schuenemann, C Avanzi, B Krause-Kyora… - PLoS …, 2018 - journals.plos.org
Studying ancient DNA allows us to retrace the evolutionary history of human pathogens,
such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the …

Pathogenicity and virulence of Mycobacterium leprae

M Sugawara-Mikami, K Tanigawa, A Kawashima… - Virulence, 2022 - Taylor & Francis
Leprosy is caused by Mycobacterium leprae (M. leprae) and M. lepromatosis, an obligate
intracellular organism, and over 200,000 new cases occur every year. M. leprae parasitizes …

2000-year-old pathogen genomes reconstructed from metagenomic analysis of Egyptian mummified individuals

J Neukamm, S Pfrengle, M Molak, A Seitz, M Francken… - BMC biology, 2020 - Springer
Background Recent advances in sequencing have facilitated large-scale analyses of the
metagenomic composition of different samples, including the environmental microbiome of …

Host diversity and origin of zoonoses: The ancient and the new

J Recht, VJ Schuenemann, MR Sánchez-Villagra - Animals, 2020 - mdpi.com
Simple Summary There is a wide variety of diseases caused by bacteria, viruses, and
parasites that are transmitted to humans by different routes from other animals. These …

Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus

AK Fotakis, SD Denham, M Mackie… - … of the Royal …, 2020 - royalsocietypublishing.org
Mineralized dental plaque (calculus) has proven to be an excellent source of ancient
biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative …

Molecular epidemiology of leprosy: An update

C Avanzi, P Singh, RW Truman, PN Suffys - Infection, Genetics and …, 2020 - Elsevier
Molecular epidemiology investigations are notoriously challenging in the leprosy field
mainly because the inherent characteristics of the disease as well as its yet uncultivated …

Comparative pathology of the peripheral nervous system

LG Lanigan, DS Russell, KD Woolard… - Veterinary …, 2021 - journals.sagepub.com
The peripheral nervous system (PNS) relays messages between the central nervous system
(brain and spinal cord) and the body. Despite this critical role and widespread distribution …

Susceptibility and resistance in leprosy: Studies in the mouse model

LB Adams - Immunological Reviews, 2021 - Wiley Online Library
Leprosy is a chronic granulomatous infectious disease caused by the pathogen,
Mycobacterium leprae, and the more recently discovered, M. lepromatosis. Described in …