Environmental influences on the epigenome: exposure-associated DNA methylation in human populations
EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …
environmental exposures. To date, numerous studies have detailed the manner by which …
Genomic imprinting disorders: lessons on how genome, epigenome and environment interact
Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …
of genes, is required for normal development, and its disruption leads to human disease …
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns
BR Joubert, HT Den Dekker, JF Felix, J Bohlin… - Nature …, 2016 - nature.com
Folate is vital for fetal development. Periconceptional folic acid supplementation and food
fortification are recommended to prevent neural tube defects. Mechanisms whereby …
fortification are recommended to prevent neural tube defects. Mechanisms whereby …
The role of epigenetic change in autism spectrum disorders
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …
disorders characterized by problems with social communication, social interaction, and …
Molecular mechanisms underlying the link between diet and DNA methylation
FZ Kadayifci, S Zheng, YX Pan - International journal of molecular …, 2018 - mdpi.com
DNA methylation is a vital modification process in the control of genetic information, which
contributes to the epigenetics by regulating gene expression without changing the DNA …
contributes to the epigenetics by regulating gene expression without changing the DNA …
DNA methylation signatures of early childhood malnutrition associated with impairments in attention and cognition
Background Early childhood malnutrition affects 113 million children worldwide, impacting
health and increasing vulnerability for cognitive and behavioral disorders later in life …
health and increasing vulnerability for cognitive and behavioral disorders later in life …
Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment
Background Interindividual epigenetic variation that occurs systemically must be established
prior to gastrulation in the very early embryo and, because it is systemic, can be assessed in …
prior to gastrulation in the very early embryo and, because it is systemic, can be assessed in …
[HTML][HTML] Epigenetic modulation of DNA methylation by nutrition and its mechanisms in animals
N Zhang - Animal nutrition, 2015 - Elsevier
It is well known that phenotype of animals may be modified by the nutritional modulations
through epigenetic mechanisms. As a key and central component of epigenetic network …
through epigenetic mechanisms. As a key and central component of epigenetic network …
Preeclampsia: from cellular wellness to inappropriate cell death, and the roles of nutrition
Preeclampsia is one of the most common obstetrical complications worldwide. The
pathomechanism of this disease begins with abnormal placentation in early pregnancy …
pathomechanism of this disease begins with abnormal placentation in early pregnancy …
The effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjects
Background Folate and its synthetic form folic acid function as donor of one-carbon units and
have been, together with other B-vitamins, implicated in programming of epigenetic …
have been, together with other B-vitamins, implicated in programming of epigenetic …