Hyaluronic acid in ocular drug delivery

X Zhang, D Wei, Y Xu, Q Zhu - Carbohydrate Polymers, 2021 - Elsevier
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

Trends in formulation approaches for sustained drug delivery to the posterior segment of the eye

A Biswas, AD Choudhury, AC Bisen, S Agrawal… - AAPS …, 2023 - Springer
The eye, an intricate organ comprising physical and physiological barriers, poses a
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …

[HTML][HTML] Sarcoidosis-related uveitis: a review

S Giorgiutti, R Jacquot, T El Jammal, A Bert… - Journal of clinical …, 2023 - mdpi.com
Sarcoidosis is an inflammatory disease that involves the eyes in 10–55% of cases,
sometimes without systemic involvement. All eye structures can be affected, but uveitis is the …

[HTML][HTML] Ocular therapeutics and molecular delivery strategies for neovascular age-related macular degeneration (Namd)

A Sarkar, V Junnuthula, S Dyawanapelly - International Journal of …, 2021 - mdpi.com
Age-related macular degeneration (AMD) is the leading cause of vision loss in geriatric
population. Intravitreal (IVT) injections are popular clinical option. Biologics and small …

[HTML][HTML] A new era in ocular therapeutics: advanced drug delivery systems for uveitis and neuro-ophthalmologic conditions

KY Wu, K Tan, D Akbar, MY Choulakian, SD Tran - Pharmaceutics, 2023 - mdpi.com
The eye's intricate anatomical barriers pose significant challenges to the penetration,
residence time, and bioavailability of topically applied medications, particularly in managing …

[HTML][HTML] Intravitreal dexamethasone implant in patients who did not complete anti-VEGF loading dose during the COVID-19 pandemic: a retrospective observational …

V Scorcia, G Giannaccare, V Gatti, S Vaccaro… - Ophthalmology and …, 2021 - Springer
Introduction To compare the functional and anatomic outcomes between eyes in patients
with diabetic macular edema (DME) who underwent a complete anti-vascular endothelial …

Implantable sustained-release drug delivery systems: A revolution for ocular therapeutics

YY Cong, B Fan, ZY Zhang, GY Li - International Ophthalmology, 2023 - Springer
Purpose Due to the inimitable anatomical structure of the eyeball and various physiological
barriers, conventional ocular local administration is often complicated by apparent …

[HTML][HTML] Overview of processed excipients in ocular drug delivery: Opportunities so far and bottlenecks

S Ashique, N Mishra, S Mohanto, BHJ Gowda, S Kumar… - Heliyon, 2023 - cell.com
Ocular drug delivery presents a unique set of challenges owing to the complex anatomy and
physiology of the eye. Processed excipients have emerged as crucial components in …

In situ gels: The next new frontier in ophthalmic drug delivery system

G Sha, J Liu, Z Jiang, M Zhu, Y Zhu… - Polymers for …, 2023 - Wiley Online Library
Recently, the eye drug delivery system has received increasing attention. The in situ
ophthalmic gel is a semisolid ophthalmic preparation that can be changed in the eyes …

[HTML][HTML] Innovative strategies for drug delivery to the ocular posterior segment

A Gabai, M Zeppieri, L Finocchio, C Salati - Pharmaceutics, 2023 - mdpi.com
Innovative and new drug delivery systems (DDSs) have recently been developed to vehicle
treatments and drugs to the ocular posterior segment and the retina. New formulations and …