[HTML][HTML] Reimagining safe lithium applications in the living environment and its impacts on human, animal, and plant system

N Shakoor, M Adeel, MA Ahmad, M Zain… - Environmental Science …, 2023 - Elsevier
Lithium's (Li) ubiquitous distribution in the environment is a rising concern due to its rapid
proliferation in the modern electronic industry. Li enigmatic entry into the terrestrial food …

Review of lithium effects on immune cells

N Maddu, PB Raghavendra - Immunopharmacology and …, 2015 - Taylor & Francis
One of the remarkable discoveries in the field of psychopharmacology from late 1940s is
Lithium (Li) that reminds of old but still gold. It continues to be a distinctive mood stabilizer …

Lithium intoxication induced pyroptosis via ROS/NF‐κB/NLRP3 inflammasome regulatory networks in kidney of mice

H Jing, F Wang, X Gao - Environmental toxicology, 2022 - Wiley Online Library
Humans and animals may be exposed to increasing contaminant lithium (Li) concentrations
in the environment with the use and disposal of Li‐containing products. Meanwhile, Li plays …

Phytochemical, antioxidant and protective effect of cactus cladodes extract against lithium-induced liver injury in rats

A Ben Saad, B Dalel, I Rjeibi, A Smida… - Pharmaceutical …, 2017 - Taylor & Francis
Context: Opuntia ficus-indica (L.) Mill.(Castaceae)(cactus) is used in Tunisian medicine for
the treatment of various diseases. Objective: This study determines phytochemical …

Antiarrhythmic effect of lithium in rats after myocardial infarction by activation of Nrf2/HO-1 signaling

TM Lee, SZ Lin, NC Chang - Free Radical Biology and Medicine, 2014 - Elsevier
Abstract Glycogen synthase kinase-3 (GSK-3) signaling has been shown to play a role in the
regulation of nuclear factor erythroid-2-related factor 2 (Nrf2), a master regulator of …

Glutathione mediated reductive activation and mitochondrial dysfunction play key roles in lithium induced oxidative stress and cytotoxicity in liver

MR Eskandari, JK Fard, MJ Hosseini, J Pourahmad - Biometals, 2012 - Springer
Lithium preparations are commonly used drug in treating mental disorders and bipolar
diseases, but metal's cytotoxic mechanisms have not yet been completely understood. In this …

[HTML][HTML] Lithium carbonate: Updated reproductive and developmental toxicity assessment using scientific literature and guideline compliant studies

K Van Deun, H Hatch, S Jacobi, W Köhl - Toxicology, 2021 - Elsevier
The current publication describes most recent so far unpublished (key) guideline and GLP
compliant reproductive and developmental toxicity studies of lithium carbonate in rats …

Lithium counteracts depressive behavior and augments the treatment effect of selective serotonin reuptake inhibitor in treatment-resistant depressed rats

K Kin, T Yasuhara, S Kawauchi, M Kameda… - Brain research, 2019 - Elsevier
Wistar Kyoto (WKY) rats are a useful animal model of treatment-resistant depression. Lithium
is effective for treating recurrent mood disorders or treatment-resistant depression, and …

[HTML][HTML] Butyrate ameliorates lithium-induced cardiometabolic disorders in male Wistar rats

AO Oyabambi, O Bamidele, AB Boluwatife - Scientific African, 2023 - Elsevier
Background Cardiometabolic disease is becoming a main cause of death worldwide with
over ten million fatalities annually. Lithium (Li) has been reported to be one of the major …

Lithium-induced hypothyroidism: oxidative stress and osmotic fragility status in rats

S Toplan, N Dariyerli, S Ozdemir, D Ozcelik… - Biological trace element …, 2013 - Springer
The present study was conducted to explore the possible effects of different doses of lithium
carbonate on thyroid functions, erythrocyte oxidant–antioxidant status, and osmotic fragility …