The genome sequences of the basidiomycete Agaricomycetes species Coprinopsis cinerea,
Laccaria bicolor, Schizophyllum commune, Phanerochaete chrysosporium, and Postia …

Tubulin, the protein subunit of microtubules (MTs), is an α/β heterodimer. In this chapter, a
hypothesis on the evolution of the tubulin molecule is proposed, based in part on recent …

The formation of primary cilia is a highly choreographed process that can be disrupted in
developing neurons by overexpressing neuromodulatory G-protein-coupled receptors …

Oxidative stress is an important part of host innate immune response to foreign pathogens,
such as bacterial LPS, but excessive activation of redox signaling may lead to pathologic …

The common neurotransmitter serotonin controls different aspects of early neuronal
differentiation, although the underlying mechanisms are poorly understood. Here we report …

Heterotrimeric G proteins typically transduce signals from G protein-coupled receptors
(GPCRs) to effector proteins. In the conventional G protein signaling paradigm, the G protein …

G proteins mediate signals from membrane G protein coupled receptors to the cell interior,
evoking significant regulation of cell physiology. The cytoskeleton contributes to cell …

In the present review, we stress the importance of the purine nucleosides, adenosine and
guanosine, in protecting the nervous system, both centrally and peripherally, via activation of …

Although evidence has shown the regulating effect of n-3 poly-unsaturated fatty acid (n-3
PUFA) on cell signaling transduction, it remains unknown whether n-3 PUFA treatment …

Activity-dependent remodeling of excitatory connections underpins memory formation in the
brain. Serotonin receptors are known to contribute to such remodeling, yet the underlying …