Role of protease and protease inhibitors in cancer pathogenesis and treatment
A Eatemadi, HT Aiyelabegan, B Negahdari… - Biomedicine & …, 2017 - Elsevier
Cancer is the second cause of death in 2015, and it has been estimated to surpass heart
diseases as the leading cause of death in the next few years. Several mechanisms are …
diseases as the leading cause of death in the next few years. Several mechanisms are …
Fungal proteases as emerging biocatalysts to meet the current challenges and recent developments in biomedical therapies: an updated review
With the increasing world population, demand for industrialization has also increased to
fulfill humans' living standards. Fungi are considered a source of essential constituents to …
fulfill humans' living standards. Fungi are considered a source of essential constituents to …
The genome of the blood fluke Schistosoma mansoni
Schistosoma mansoni is responsible for the neglected tropical disease schistosomiasis that
affects 210 million people in 76 countries. Here we present analysis of the 363 megabase …
affects 210 million people in 76 countries. Here we present analysis of the 363 megabase …
Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV
Two viral proteases of severe acute respiratory syndrome coronavirus (SARS-CoV), a
chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro) are attractive …
chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro) are attractive …
Combating enterovirus replication: state-of-the-art on antiviral research
HJ Thibaut, AM De Palma, J Neyts - Biochemical pharmacology, 2012 - Elsevier
Enteroviruses form an important genus within the large family of Picornaviridae. They are
small, non-enveloped (+) RNA viruses, many of which are important pathogens in human …
small, non-enveloped (+) RNA viruses, many of which are important pathogens in human …
[HTML][HTML] Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
P Goettig, V Magdolen, H Brandstetter - Biochimie, 2010 - Elsevier
Including the true tissue kallikrein KLK1, kallikrein-related peptidases (KLKs) represent a
family of fifteen mammalian serine proteases. While the physiological roles of several KLKs …
family of fifteen mammalian serine proteases. While the physiological roles of several KLKs …
Current status and perspectives of protease inhibitors and their combination with nanosized drug delivery systems for targeted cancer therapy
M Rudzińska, C Daglioglu, LV Savvateeva… - Drug design …, 2021 - Taylor & Francis
In cancer treatments, many natural and synthetic products have been examined; among
them, protease inhibitors are promising candidates for anti-cancer agents. Since …
them, protease inhibitors are promising candidates for anti-cancer agents. Since …
Intestinal exposure to food-derived protease inhibitors: digestion physiology-and gut health-related effects
A Kårlund, I Paukkonen, C Gómez-Gallego… - Healthcare, 2021 - mdpi.com
Plant-derived protease inhibitors (PI), such as Bowman-Birk inhibitors and Kunitz-type
inhibitors, have been suggested to negatively affect dietary protein digestion by blocking the …
inhibitors, have been suggested to negatively affect dietary protein digestion by blocking the …
Viral protease inhibitors
This review provides an overview of the development of viral protease inhibitors as antiviral
drugs. We concentrate on HIV-1 protease inhibitors, as these have made the most significant …
drugs. We concentrate on HIV-1 protease inhibitors, as these have made the most significant …
Biocatalytic synthesis of flavonoid esters by lipases and their biological benefits
MEMB de Araújo, YEM Franco, MCF Messias… - Planta …, 2017 - thieme-connect.com
Several studies have described important biological activities of flavonoids such as coronary
heart disease prevention, hepatoprotective, anti-inflammatory and anticancer activities …
heart disease prevention, hepatoprotective, anti-inflammatory and anticancer activities …