Single and collective cell migration are fundamental processes critical for physiological
phenomena ranging from embryonic development and immune response to wound healing …

Cell imaging has entered the 'Big Data'era. New technologies in light microscopy and
molecular biology have led to an explosion in high-content, dynamic and multidimensional …

Deep learning is now a powerful tool in microscopy data analysis, and is routinely used for
image processing applications such as segmentation and denoising. However, it has rarely …

Neutrophils are the most abundant leukocyte in humans and provide a critical early line of
defense as part of our innate immune system. We perform a comprehensive, genome-wide …

Live-cell imaging experiments have opened an exciting window into the behavior of living
systems. While these experiments can produce rich data, the computational analysis of …

Cell and organelle shape are driven by diverse genetic and environmental factors and thus
accurate quantification of cellular morphology is essential to experimental cell biology …

Medicines and agricultural biocides are often discovered using large phenotypic screens
across hundreds of compounds, where visible effects of whole organisms are compared to …

A cell's shape and motion represent fundamental aspects of cell identity and can be highly
predictive of function and pathology. However, automated analysis of the morphodynamic …

Neutrophils are the most abundant leukocyte in humans and provide a critical early line of
defense as part of our innate immune system. Their exquisite sensitivity to chemical …

Understanding morphological variation is an important task in many areas of computational
biology. Recent studies have focused on developing computational tools for the task of sub …