Regulation of inflammatory cytokines for spinal cord injury repair through local delivery of therapeutic agents

H Ren, X Chen, M Tian, J Zhou, H Ouyang… - Advanced …, 2018 - Wiley Online Library
The balance of inflammation is critical to the repair of spinal cord injury (SCI), which is one of
the most devastating traumas in human beings. Inflammatory cytokines, the direct mediators …

Anatomy of the olfactory mucosa

I Salazar, P Sanchez-Quinteiro, AW Barrios… - Handbook of clinical …, 2019 - Elsevier
The classic notion that humans are microsmatic animals was born from comparative
anatomy studies showing the reduction in the size of both the olfactory bulbs and the limbic …

Safety and feasibility of autologous olfactory ensheathing cell and bone marrow mesenchymal stem cell co-transplantation in chronic human spinal cord injury: a …

H Zamani, M Soufizomorrod, S Oraee-Yazdani… - Spinal Cord, 2022 - nature.com
Study design This is a phase I clinical trial. Objectives Our objective was to assess the safety
and feasibility of autologous mucosal olfactory ensheathing cell (OEC) and bone marrow …

The effects of co-transplantation of olfactory ensheathing cells and Schwann cells on local inflammation environment in the contused spinal cord of rats

J Zhang, H Chen, Z Duan, K Chen, Z Liu, L Zhang… - Molecular …, 2017 - Springer
Inflammatory response following spinal cord injury (SCI) is important in regulation of the
repair process. Olfactory ensheathing cells (OECs) and Schwann cells (SCs) are important …

Cranial pair I: the olfactory nerve

C Crespo, T Liberia, JM Blasco‐Ibáñez… - The Anatomical …, 2019 - Wiley Online Library
The olfactory nerve constitutes the first cranial pair. Compared with other cranial nerves, it
depicts some atypical features. First, the olfactory nerve does not form a unique bundle. The …

Roles of Runx Genes in Nervous System Development

JW Wang, S Stifani - RUNX Proteins in Development and Cancer, 2017 - Springer
Runt-related (Runx) transcription factors play essential roles during development and adult
tissue homeostasis and are responsible for several human diseases. They regulate a variety …

Remyelination and multiple sclerosis: therapeutic approaches and challenges

MD Hartley, G Altowaijri, D Bourdette - Current neurology and …, 2014 - Springer
Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous
system. After acute inflammatory mediated demyelination, some remyelination often occurs …

Glucagon-like peptide-1 receptor agonists as potential myelination-inducible and anti-demyelinating remedies

K Sango, S Takaku, M Tsukamoto, N Niimi… - Frontiers in Cell and …, 2022 - frontiersin.org
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) were developed as insulinotropic
and anti-hyperglycemic agents for the treatment of type 2 diabetes, but their neurotrophic …

Li+ activated nanohydroxyapatite doped with Eu3+ ions enhances proliferative activity and viability of human stem progenitor cells of adipose tissue and olfactory …

K Marycz, P Sobierajska, A Smieszek… - Materials Science and …, 2017 - Elsevier
Spinal cord injuries (SCI) often require simultaneous regeneration of nerve tissue and bone.
Hydroxyapatites are described as bioresorbable materials with proper biocompatibility and …

Transplantation of Cryopreserved Olfactory Ensheathing Cells Restores Loss of Functions in an Experimental Model

K Minkelyte, D Li, Y Li, A Ibrahim - Cell Transplantation, 2023 - journals.sagepub.com
In the past decades, the properties of olfactory ensheathing cells (OECs) have been widely
investigated. Studies have shown that transplantation of OECs cultured from the olfactory …