Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

Changes in DNA methylation have been causally linked with cancer and provide promising
biomarkers for detection in biological fluids such as blood, urine, and saliva. The field has …

Back ground Systematic reviews have concluded that hrHPV DNA testing using target-
amplification tests is as accurate on vaginal self-samples as on clinician-taken specimens …

Abstract Background Lung (LC), prostate (PCa) and colorectal (CRC) cancers are the most
incident in males worldwide. Despite recent advances, optimal population-based cancer …

Background The incidence of endometrial cancer is rising, and current diagnostics often
require invasive biopsy procedures. Urine may offer an alternative sample type, which is …

Differentially methylated CpG sites (dmCpGs) that distinguish prostate tumour from adjacent
benign tissue could aid in the diagnosis and prognosis of prostate cancer. Previously, the …

Simple Summary Prostate cancer (PCa) is the most frequent malignancy, and the second
leading cause of cancer-related death, in men in the United States. PCa detection has been …

Conrad Waddington's theory of epigenetic landscape epitomize the process of cell fate and
cellular decision-making during development. Wherein the epigenetic code maintains …

Background Significant numbers of prostate cancer (PCa) patients experience tumour
upstaging and upgrading in surgical specimens that cause serious problems in timely and …

Simple Summary Prostate cancer is a heterogeneous disease and a major cause of cancer
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …