The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

From wedding rings on fingers to stained glass windows, by way of Olympic medals, gold
has been highly prized for millennia. Nowadays, organometallic gold compounds occupy an …

A new series of gold (I) N-heterocyclic carbene (NHC) complexes based on xanthine ligands
have been synthesized and characterized by mass spectrometry, NMR, and X-ray diffraction …

The four natural DNA bases (A, T, G and C) associate in base pairs (A= T and G≡ C),
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …

For over two decades, the prime objective of the chemical biology community studying G-
quadruplexes (G4s) has been to use chemicals to interact with and stabilize G4s in cells to …

The dicarbene gold (I) complex [Au (9‐methylcaffein‐8‐ylidene) 2] BF4 is an exceptional
organometallic compound of profound interest as a prospective anticancer agent. This gold …

Since their first discovery, N-heterocyclic carbenes have had a significant impact on
organometallic chemistry. Due to their nature as strong σ-donor and π-acceptor ligands, they …

Metal complexes of N-heterocyclic carbene (NHC) ligands are the object of increasing
attention for therapeutic purposes. Among the different metal centres, interest on Au-based …

Damaging DNA is a current and efficient strategy to fight against cancer cell proliferation.
Numerous mechanisms exist to counteract DNA damage, collectively referred to as the DNA …

Conspectus Biomimetics is defined as a “practice of making technological design that copies
natural processes”, with the idea that “nature has already solved the challenges we are …