[HTML][HTML] Sepsis-induced coagulopathy: an update on pathophysiology, biomarkers, and current guidelines

AG Tsantes, S Parastatidou, EA Tsantes, E Bonova… - Life, 2023 - mdpi.com
Significant cross talk occurs between inflammation and coagulation. Thus, coagulopathy is
common in sepsis, potentially aggravating the prognosis. Initially, septic patients tend to …

[HTML][HTML] Hemostatic challenges in neonates

P Davenport, M Sola-Visner - Frontiers in pediatrics, 2021 - frontiersin.org
The neonatal hemostatic system is strikingly different from that of adults. Among other
differences, neonates exhibit hyporeactive platelets and decreased levels of coagulation …

The use of thromboelastography (TEG) and rotational thromboelastometry (ROTEM) in neonates: a systematic review

GΝ Katsaras, R Sokou, AG Tsantes, D Piovani… - European Journal of …, 2021 - Springer
Abstract “Developmental hemostasis” refers to the dynamic process of gradual hemostatic
maturation. Conventional coagulation tests seem to fail to accurately depict the in vivo …

[HTML][HTML] Development and validation of a sepsis diagnostic scoring model for neonates with suspected sepsis

R Sokou, G Ioakeimidis, D Piovani… - Frontiers in …, 2022 - frontiersin.org
Background We aimed to develop and validate a diagnostic model for sepsis among
neonates evaluated for suspected sepsis, by incorporating thromboelastometry parameters …

Fresh frozen plasma transfusion in the neonatal population: a systematic review

R Sokou, S Parastatidou, A Konstantinidi, AG Tsantes… - Blood Reviews, 2022 - Elsevier
Although fresh frozen plasma (FFP) transfusions are common practice in neonatology,
robust evidence on their use is lacking. The aim of this study was to systematically review …

Assessment of hemostatic profile in neonates with necrotizing enterocolitis using rotational thromboelastometry (ROTEM)

R Sokou, P Mantzios, AG Tsantes, S Parastatidou… - Pediatric …, 2024 - nature.com
Background This study aimed to explore the hemostatic profile of neonates with necrotizing
enterocolitis (NEC) using Rotational Thromboelastometry (ROTEM) and to investigate if …

[HTML][HTML] The haemostatic profile in critically ill COVID-19 patients receiving therapeutic anticoagulant therapy: An observational study

AE Tsantes, F Frantzeskaki, AG Tsantes, E Rapti… - Medicine, 2020 - journals.lww.com
The haemostatic profile in critically ill COVID-19 patients... : Medicine The haemostatic profile in
critically ill COVID-19 patients receiving therapeutic anticoagulant therapy: An observational …

Rotational thromboelastometry in neonates admitted to a neonatal intensive care unit: a large cross-sectional study

R Sokou, AG Tsantes, A Konstantinidi… - … in Thrombosis and …, 2021 - thieme-connect.com
The aim of the present study was to assess the coagulation profile in neonatal critical illness
using rotational thromboelastometry (ROTEM), and to investigate its association with …

[HTML][HTML] COVID-19 infection-related coagulopathy and viscoelastic methods: a paradigm for their clinical utility in critical illness

AE Tsantes, AG Tsantes, SI Kokoris, S Bonovas… - Diagnostics, 2020 - mdpi.com
Hypercoagulability and thrombosis remain a challenge to diagnose and treat in severe
COVID-19 infection. The ability of conventional global coagulation tests to accurately reflect …

Contemporary tools for evaluation of hemostasis in neonates. Where are we and where are we headed?

R Sokou, S Parastatidou, A Konstantinidi, AG Tsantes… - Blood Reviews, 2023 - Elsevier
The assessment of hemostatic disorders in neonates is crucial, but remains challenging for
clinicians. Although the concept of developmental hemostasis is widely accepted among …