This review article highlights the strategies to successfully perform an efficient solid-phase
synthesis of complex peptides including posttranslational modifications, fluorescent labels …

Inositol pyrophosphates (IPPs) are present in organisms ranging from plants, slime moulds
and fungi to mammals. Distinct classes of kinases generate different forms of energetic …

Reversible protein phosphorylation is a major mechanism in the regulation of fundamental
signalling events in all living organisms. Bacteria have been shown to possess a versatile …

Abstract Targeted Protein Modification (TPM) is an umbrella term encompassing numerous
tools and approaches that use bifunctional agents to induce a desired modification over the …

Little is known about virus adaptation in immunocompromised patients with chronic
genotype 3 hepatitis E virus (HEV3) infections. Virus-host recombinant strains have been …

Phosphorylation under plausible prebiotic conditions continues to be one of the defining
issues for the role of phosphorus in the origins of life processes. In this review, we cover the …

For centuries, crop plants have represented the basis of the daily human diet. Among them,
cereals and legumes, accumulating oils, proteins, and carbohydrates in their seeds …

Tyrosine Phosphorylation (pTyr) is a critical and ubiquitous regulation mechanism in biology
that plays a central role in controlling intracellular signaling networks. Precise recognition …

Adherens junctions connect the actin cytoskeleton of neighboring cells through
transmembrane cadherin receptors and a network of adaptor proteins. The interactions …

Protein phosphorylation is a modification that offers a dynamic and reversible mechanism to
regulate the majority of cellular processes. Numerous diseases are associated with aberrant …