Transforming growth factor β (TGF-β) has long been identified with its intensive involvement
in early embryonic development and organogenesis, immune supervision, tissue repair, and …

Fibrosis refers to the excessive deposition of extracellular matrix components in the
processes of wound repair or tissue regeneration after tissue damage. Fibrosis occurs in …

Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in
inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic regulator for promoting …

Systemic sclerosis (SSc) is a prototypical inflammatory fibrotic disease involving
inflammation, vascular abnormalities and fibrosis that primarily affect the skin and lungs. The …

Transforming growth factor‐β (TGF‐β) is a proinflammatory cytokine known to control a
diverse array of pathological and physiological conditions during normal development and …

Systemic sclerosis is a rare and chronic connective tissue disease with a multifaceted
pathogenesis characterised by heterogeneous multi-organ clinical manifestations. Every …

Idiopathic pulmonary fibrosis is a progressive lung disease of unknown etiology
characterized by distorted distal lung architecture, inflammation, and fibrosis. Several lung …

Air pollution is highly associated with respiratory diseases. However, the influence and
mechanism of particulate matter with aerodynamic equal to or less than 2.5 μm (PM 2.5) in …

Genome-wide analyses have revealed that long noncoding RNAs (lncRNAs) are not only
passive transcription products, but also major regulators of genome structure and …

MicroRNAs (miR), as important epigenetic control factors, reportedly regulate wound repair.
However, our insufficient knowledge of clinically relevant miRs hinders their potential …