• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Background The optimal index of microvascular function should be specific for the
microvascular compartment. Yet, coronary flow reserve (CFR), despite being widely used to …

Angiography-derived fractional flow reserve (FFR) has emerged as a non-invasive
technique to assess the functional significance of coronary artery stenoses. The clinical …

Background Coronary physiology measured by fractional flow reserve (FFR) is superior to
angiography for assessing the efficacy of percutaneous coronary intervention (PCI). Yet, the …

Abstract Background and Aims The microvascular resistance reserve (MRR) is a novel
invasive index of the microcirculation, which is independent of epicardial stenoses, and has …

Background Fluid-filled pressure guidewires are unaffected by the previously inevitable
hydrostatic pressure gradient (HPG). This study aimed to compare simultaneous pressure …

Abstract Background AccuFFRct (ArteryFlow Technology) is a novel noninvasive method for
calculating fractional flow reserve (FFR) from coronary computed tomography angiography …

Background Discrepancies between stenosis severity assessed at coronary computed
tomography angiography (CCTA) and ischemia might depend on vessel type. Coronary …

Background Fractional flow reserve (FFR) has emerged as the invasive gold standard for
assessing vessel‐specific ischemia. However, FFR measurements are influenced by the …

Invasive coronary physiology is well-established for identifying stable lesions appropriate for
revascularization with percutaneous coronary intervention (PCI). Furthermore, fractional flow …