The presence of an abnormal amount of single-stranded DNA in the bacterial cell constitutes
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …

Approximately 10% of bacterial genomes are split between two or more large DNA
fragments, a genome architecture referred to as a multipartite genome. This multipartite …

Highlights•Bacterial genomes contain C 5-methyl-cytosine, N 4-methyl-cytosine, and N 6-
methyl-adenine.•Base methylation controls DNA–protein interactions.•DNA methylation …

Epigenetics is a change in gene expression that is heritable without a change in DNA
sequence itself. This phenomenon is well studied in eukaryotes, particularly in humans for …

Bacteria with multiple chromosomes represent up to 10% of all bacterial species. Unlike
eukaryotes, these bacteria use chromosome-specific initiators for their replication. In all …

Epigenetics modulates expression levels of various important genes in both prokaryotes and
eukaryotes. These epigenetic traits are heritable without any change in genetic DNA …

To preserve the integrity of their genome, bacteria rely on several genome maintenance
mechanisms that are co-ordinated with the cell cycle. All members of the Vibrio family have a …

Unlike eukaryotes and archaea, which have multiple replication origins on their
chromosomes, bacterial chromosomes usually contain a single replication origin. 1 Here, we …

Summary It was Barbara McClintock who first described the problems of segregation arising
from the circularity of chromosomes during her studies on maize variegation (1). The …

Faithful vertical transmission of genetic information, especially of essential core genes, is a
prerequisite for bacterial survival. Hence, replication of all the replicons is tightly controlled …