Small‐molecule prodrug nanoassemblies: an emerging nanoplatform for anticancer drug delivery
G Li, B Sun, Y Li, C Luo, Z He, J Sun - Small, 2021 - Wiley Online Library
The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …
restricted by low drug loading, complex preparation technology, and potential toxicity …
Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Diverse applications of nanomedicine
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …
health-related issues continues to receive increasing interest. Research in nanomedicine …
Self-assembled redox dual-responsive prodrug-nanosystem formed by single thioether-bridged paclitaxel-fatty acid conjugate for cancer chemotherapy
Chemotherapeutic efficacy can be greatly improved by developing nanoparticulate drug
delivery systems (nano-DDS) with high drug loading capacity and smart stimulus-triggered …
delivery systems (nano-DDS) with high drug loading capacity and smart stimulus-triggered …
Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease
F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …
ROS stress in cancer cells and therapeutic implications
H Pelicano, D Carney, P Huang - Drug resistance updates, 2004 - Elsevier
Reactive oxygen species (ROS) are constantly generated and eliminated in the biological
system, and play important roles in a variety of normal biochemical functions and abnormal …
system, and play important roles in a variety of normal biochemical functions and abnormal …
Mitochondrial metabolism of reactive oxygen species
AY Andreyev, YE Kushnareva, AA Starkov - Biochemistry (Moscow), 2005 - Springer
Oxidative stress is considered a major contributor to etiology of both “normal” senescence
and severe pathologies with serious public health implications. Mitochondria generate …
and severe pathologies with serious public health implications. Mitochondria generate …
[PDF][PDF] Oxidative stress: animal adaptations in nature
KB Storey - Brazilian journal of medical and biological research, 1996 - researchgate.net
As a consequence of aerobic life, an organism must deal with the continuous generation of
reactive oxygen species (O2-, H2O2,• OH) as byproducts of metabolism and defend itself …
reactive oxygen species (O2-, H2O2,• OH) as byproducts of metabolism and defend itself …
Tumor redox heterogeneity‐responsive prodrug nanocapsules for cancer chemotherapy
Nanocarriers have been extensively explored for cancer drug delivery to increase the
solubility of the drug in water [1] and tumor accumulation [2] by means of its enhanced …
solubility of the drug in water [1] and tumor accumulation [2] by means of its enhanced …
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
N Zamzami, P Marchetti, M Castedo… - The Journal of …, 1995 - rupress.org
Programmed cell death (PCD) is a physiological process commonly defined by alterations in
nuclear morphology (apoptosis) and/or characteristic stepwise degradation of chromosomal …
nuclear morphology (apoptosis) and/or characteristic stepwise degradation of chromosomal …