BACKGROUND: To reduce transmission and improve patient outcomes, rapid diagnosis
and treatment of rifampicin-resistant tuberculosis (RR-TB) is required. OBJECTIVE: To …

Background Several reviews on the accuracy of Tuberculosis (TB) Nucleic Acid
Amplification Tests (NAATs) have been performed but the evidence on their impact on …

Rates and risk factors for acquired drug resistance and association with outcomes among
patients with multidrug-resistant tuberculosis (MDR TB) are not well defined. In an MDR TB …

Background There is an urgent demand for rapid and accurate drug-susceptibility testing for
the detection of multidrug-resistant tuberculosis. The GenoType MTBDR plus assay is a …

Telomere length is a promising biomarker for age-associated diseases and cancer, but there
are still substantial challenges to routine telomere analysis in clinics because of the lack of a …

Although molecular tests for drug-resistant TB perform well on culture isolates, their
accuracy using clinical samples, particularly from TB and HIV-endemic settings, requires …

The metabolic signaling pathways that drive pathologic tissue inflammation and damage in
humans with pulmonary tuberculosis (TB) are not well understood. Using combined …

En las últimas 2 décadas la tuberculosis con resistencia a fármacos se ha convertido en una
amenaza y un reto para la salud pública mundial. El diagnóstico y el tratamiento de estas …

In the last 2 decades, drug-resistant tuberculosis has become a threat and a challenge to
worldwide public health. The diagnosis and treatment of these forms of tuberculosis are …

In high tuberculosis (TB)-burden countries such as China, the diagnosis of multidrug-
resistant tuberculosis (MDR-TB) using conventional drug susceptibility testing (DST) takes …