Endogenous microRNA sponges: evidence and controversy
DW Thomson, ME Dinger - Nature Reviews Genetics, 2016 - nature.com
The competitive endogenous RNA (ceRNA) hypothesis proposes that transcripts with
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
Tools for sequence-based miRNA target prediction: what to choose?
ÁL Riffo-Campos, I Riquelme… - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are defined as small non-coding RNAs~ 22 nt in length. They regulate
gene expression at a post-transcriptional level through complementary base pairing with the …
gene expression at a post-transcriptional level through complementary base pairing with the …
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues
MicroRNAs (miRNAs) regulate target mRNAs through a combination of translational
repression and mRNA destabilization, with mRNA destabilization dominating at steady state …
repression and mRNA destabilization, with mRNA destabilization dominating at steady state …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
[HTML][HTML] MicroRNAs: target recognition and regulatory functions
DP Bartel - cell, 2009 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 23 nt RNAs that play important gene-regulatory
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
The functions of animal microRNAs
V Ambros - Nature, 2004 - nature.com
MicroRNAs (miRNAs) are small RNAs that regulate the expression of complementary
messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and …
messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and …
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
BP Lewis, CB Burge, DP Bartel - cell, 2005 - cell.com
We predict regulatory targets of vertebrate microRNAs (miRNAs) by identifying mRNAs with
conserved complementarity to the seed (nucleotides 2–7) of the miRNA. An …
conserved complementarity to the seed (nucleotides 2–7) of the miRNA. An …
Oncomirs—microRNAs with a role in cancer
A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …
Combinatorial microRNA target predictions
MicroRNAs are small noncoding RNAs that recognize and bind to partially complementary
sites in the 3′ untranslated regions of target genes in animals and, by unknown …
sites in the 3′ untranslated regions of target genes in animals and, by unknown …
Human microRNA targets
MicroRNAs (miRNAs) interact with target mRNAs at specific sites to induce cleavage of the
message or inhibit translation. The specific function of most mammalian miRNAs is …
message or inhibit translation. The specific function of most mammalian miRNAs is …