Physical cues of biomaterials guide stem cell differentiation fate

A Higuchi, QD Ling, Y Chang, ST Hsu… - Chemical …, 2013 - ACS Publications
Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …

A critical review of fibrous polyurethane-based vascular tissue engineering scaffolds

S Fathi-Karkan, B Banimohamad-Shotorbani… - Journal of biological …, 2022 - Springer
Certain polymeric materials such as polyurethanes (PUs) are the most prevalent class of
used biomaterials in regenerative medicine and have been widely explored as vascular …

Polypyrrole/alginate hybrid hydrogels: electrically conductive and soft biomaterials for human mesenchymal stem cell culture and potential neural tissue engineering …

S Yang, LK Jang, S Kim, J Yang, K Yang… - Macromolecular …, 2016 - Wiley Online Library
Electrically conductive biomaterials that can efficiently deliver electrical signals to cells or
improve electrical communication among cells have received considerable attention for …

Scaffolds from self-assembling tetrapeptides support 3D spreading, osteogenic differentiation, and angiogenesis of mesenchymal stem cells

S Alshehri, HH Susapto, CAE Hauser - Biomacromolecules, 2021 - ACS Publications
The apparent rise of bone disorders demands advanced treatment protocols involving tissue
engineering. Here, we describe self-assembling tetrapeptide scaffolds for the growth and …

Compressive elasticity of three-dimensional nanofiber matrix directs mesenchymal stem cell differentiation to vascular cells with endothelial or smooth muscle cell …

K Wingate, W Bonani, Y Tan, SJ Bryant, W Tan - Acta biomaterialia, 2012 - Elsevier
The importance of mesenchymal stem cells (MSC) in vascular regeneration is becoming
increasingly recognized. However, few in vitro studies have been performed to identify the …

Mesenchymal stem cells for vascular regeneration

NF Huang, S Li - Regenerative medicine, 2008 - Taylor & Francis
Mesenchymal stem cells (MSCs) have tremendous potential for regenerative medicine, and
have been researched for the treatment of cardiovascular diseases. MSCs are a promising …

Adult stem cell-based tissue engineered blood vessels: a review

JT Krawiec, DA Vorp - Biomaterials, 2012 - Elsevier
With the high occurrence of cardiovascular disease and increasing numbers of patients
requiring vascular access, there is a significant need for a small-diameter (< 6 mm inner …

Biomimetic control of vascular smooth muscle cell morphology and phenotype for functional tissue‐engineered small‐diameter blood vessels

MB Chan‐Park, JY Shen, Y Cao… - … Research Part A: An …, 2009 - Wiley Online Library
Small‐diameter blood vessel substitutes are urgently needed for patients requiring
replacements of their coronary and below‐the‐knee vessels and for better arteriovenous …

Combining Dynamic Stretch and Tunable Stiffness to Probe Cell Mechanobiology In Vitro

AM Throm Quinlan, LN Sierad, AK Capulli… - PloS one, 2011 - journals.plos.org
Cells have the ability to actively sense their mechanical environment and respond to both
substrate stiffness and stretch by altering their adhesion, proliferation, locomotion …

The synergetic effect of hydrogel stiffness and growth factor on osteogenic differentiation

SJ Tan, JY Fang, Z Yang, ME Nimni, B Han - Biomaterials, 2014 - Elsevier
Cells respond to various chemical signals as well as environmental aspects of the
extracellular matrix (ECM) that may alter cellular structures and functions. Hence, better …