Rodent models in neuroscience research: is it a rat race?

B Ellenbroek, J Youn - Disease models & mechanisms, 2016 - journals.biologists.com
Rodents (especially Mus musculus and Rattus norvegicus) have been the most widely used
models in biomedical research for many years. A notable shift has taken place over the last …

LPS-induced murine neuroinflammation model: main features and suitability for pre-clinical assessment of nutraceuticals

M Nava Catorce, G Gevorkian - Current neuropharmacology, 2016 - ingentaconnect.com
Neuroinflammation is an important feature in the pathogenesis and progression of
neurodegenerative diseases such as Alzheimer´ s disease (AD), Parkinson´ s disease (PD) …

[图书][B] What comes after entanglement?: Activism, anthropocentrism, and an ethics of exclusion

EH Giraud - 2019 - books.google.com
By foregrounding the ways that human existence is bound together with the lives of other
entities, contemporary cultural theorists have sought to move beyond an anthropocentric …

[HTML][HTML] Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity

D Val-Laillet, E Aarts, B Weber, M Ferrari… - NeuroImage: Clinical, 2015 - Elsevier
Functional, molecular and genetic neuroimaging has highlighted the existence of brain
anomalies and neural vulnerability factors related to obesity and eating disorders such as …

Animal models of Parkinson's disease

EA Konnova, M Swanberg - Exon Publications, 2018 - exonpublications.com
Parkinson's disease (PD) is a heterogenous disease with a varying age of onset, symptoms,
and rate of progression. This heterogeneity requires the use of a variety of animal models to …

Alpha-synuclein and tau: teammates in neurodegeneration?

S Moussaud, DR Jones… - Molecular …, 2014 - Springer
The accumulation of α-synuclein aggregates is the hallmark of Parkinson's disease, and
more generally of synucleinopathies. The accumulation of tau aggregates however is …

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

S Srivastav, S Neupane, S Bhurtel, N Katila… - The Journal of …, 2019 - Elsevier
Microbiota in the gut affect brain physiology via various pathways, and dysbiosis seems to
play a role in the pathogenesis of Parkinson's disease (PD). Probiotics showed pleiotropic …

Brain insulin resistance: role in neurodegenerative disease and potential for targeting

C Hölscher - Expert opinion on investigational drugs, 2020 - Taylor & Francis
Introduction: This review evaluates the novel strategy of treating Alzheimer's and Parkinson's
disease (AD and PD) withdrugs that initially have been developed to treat type 2 diabetes …

PINK1, Parkin, and mitochondrial quality control: what can we learn about Parkinson's disease pathobiology?

D Truban, X Hou, TR Caulfield… - Journal of …, 2017 - content.iospress.com
The first clinical description of Parkinson's disease (PD) will embrace its two century
anniversary in 2017. For the past 30 years, mitochondrial dysfunction has been …

The role of innate and adaptive immunity in Parkinson's disease

GT Kannarkat, JM Boss… - Journal of Parkinson's …, 2013 - content.iospress.com
In recent years, inflammation has become implicated as a major pathogenic factor in the
onset and progression of Parkinson's disease. Understanding the precise role for …