Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Although the administration of fluid is the first treatment considered in almost all cases of
circulatory failure, this therapeutic option poses two essential problems: the increase in …

Background Fluid and vasopressor management in septic shock remains controversial. In
this randomized controlled trial, we evaluated the efficacy of dynamic measures (stroke …

Background Fluid therapy—the administration of fluids to maintain adequate organ tissue
perfusion and oxygenation—is essential in patients admitted to the intensive care unit (ICU) …

Objective Administration of diuretics has been shown to assist fluid management and
improve clinical outcomes in the critically ill post-shock resolution. Current guidelines have …

Purpose This is the second article in a 2-part series discussing the pathophysiology of
sepsis. Part 1 of the series reviewed the immunologic response and overlapping pathways …

Acute respiratory distress syndrome (ARDS) is a severe organ failure occurring mainly in
critically ill patients as a result of different types of insults such as sepsis, trauma or …

Sepsis: an overview of the signs, symptoms, diagnosis, treatment and pathophysiology
Page 1 emergencynurse.co.uk | PEER-REVIEWED | evidence & practice /CPD /urgent care …

Background and aims Assessment of the raw parameters derived from bioelectrical
impedance analysis (BIA) has gained emphasis in critically ill patients. The phase angle …

Background Injury to endothelium and glycocalyx predisposes to vascular leak, which may
subsequently lead to increased fluid requirements and worse outcomes. In this post hoc …