The long-dreamed-of capability of monitoring the molecular machinery in living systems has
not been realized yet, mainly due to the technical limitations of current sensing technologies …

After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …

Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Ever since the inception of light microscopy, the laws of physics have seemingly thwarted
every attempt to visualize the processes of life at its most fundamental, sub-cellular, level …

To extract from an image of a single nanoscale object maximum physical information about
its position, we propose and demonstrate a framework for pupil-plane modulation for 3D …

Fluorescence provides a mechanism for achieving contrast in biological imaging that
enables investigations of molecular structure, dynamics, and function at high spatial and …

We employ a novel framework for information-optimal microscopy to design a family of point
spread functions (PSFs), the Tetrapod PSFs, which enable high-precision localization of …

Super-resolution microscopy has revolutionized cellular imaging in recent years,,,. Methods
that rely on sequential localization of single point emitters enable spatial tracking at a …

New developments in the microrheology of complex fluids are considered. Firstly the
requirements for a simple modern particle tracking microrheology experiment are …

Controlling the propagation and coupling of light to sub-wavelength antennas is a crucial
prerequisite for many nanoscale optical devices. Recently, the main focus of attention has …