The 'ForensOMICS'approach for postmortem interval estimation from human bone by integrating metabolomics, lipidomics, and proteomics
The combined use of multiple omics allows to study complex interrelated biological
processes in their entirety. We applied a combination of metabolomics, lipidomics and …
processes in their entirety. We applied a combination of metabolomics, lipidomics and …
Systematic review on post-mortem protein alterations: Analysis of experimental models and evaluation of potential biomarkers of time of death
MA Sacco, F Cordasco, C Scalise, P Ricci, I Aquila - Diagnostics, 2022 - mdpi.com
Estimating the post-mortem interval (PMI) is a very complex issue due to numerous variables
that may affect the calculation. Several authors have investigated the quantitative and …
that may affect the calculation. Several authors have investigated the quantitative and …
An interdisciplinary forensic approach for human remains identification and missing persons investigations
A Dahal, D McNevin, M Chikhani… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
The resolution of unidentified human remains (UHR) and long‐term missing persons (LTMP)
cases is paramount for administrative, legal, and humanitarian reasons. There are various …
cases is paramount for administrative, legal, and humanitarian reasons. There are various …
Estimating the time of human decomposition based on skeletal muscle biopsy samples utilizing an untargeted LC–MS/MS-based proteomics approach
Accurate estimation of the postmortem interval (PMI) is crucial in forensic medico-legal
investigations to understand case circumstances (eg narrowing down list of missing persons …
investigations to understand case circumstances (eg narrowing down list of missing persons …
Phylobone: a comprehensive database of bone extracellular matrix proteins in human and model organisms
M Fontcuberta-Rigo, M Nakamura, P Puigbò - Bone Research, 2023 - nature.com
The bone extracellular matrix (ECM) contains minerals deposited on highly crosslinked
collagen fibrils and hundreds of non-collagenous proteins. Some of these proteins are key to …
collagen fibrils and hundreds of non-collagenous proteins. Some of these proteins are key to …
Insights into the differential preservation of bone proteomes in inhumed and entombed cadavers from Italian forensic caseworks
A Bonicelli, A Di Nunzio, C Di Nunzio… - Journal of Proteome …, 2022 - ACS Publications
Bone is a hard biological tissue and a precious reservoir of information in forensic
investigations as it retains key biomolecules commonly used for identification purposes …
investigations as it retains key biomolecules commonly used for identification purposes …
The Texas state donated skeletal collection at the forensic anthropology center at Texas state
The Forensic Anthropology Center at Texas State (FACTS) began accepting whole-body
donations for scientific research and educational purposes under the Texas Anatomical Gift …
donations for scientific research and educational purposes under the Texas Anatomical Gift …
A novel method for determining postmortem interval based on the metabolomics of multiple organs combined with ensemble learning techniques
X Lu, J Li, X Wei, N Li, L Dang, G An, Q Du… - International Journal of …, 2023 - Springer
Determining postmortem interval (PMI) is one of the most challenging and essential
endeavors in forensic science. Developments in PMI estimation can take advantage of …
endeavors in forensic science. Developments in PMI estimation can take advantage of …
Molecular signatures written in bone proteins of 79 AD victims from Herculaneum and Pompeii
An extensive proteomic analysis was performed on a set of 12 bones of human victims of the
eruption that in AD 79 rapidly buried Pompeii and Herculaneum, allowing the detection of …
eruption that in AD 79 rapidly buried Pompeii and Herculaneum, allowing the detection of …
Identification of gravity-responsive proteins in the femur of spaceflight mice using a quantitative proteomic approach
K Egashira, Y Ino, Y Nakai, T Ohira, T Akiyama… - Journal of …, 2023 - Elsevier
Although the microgravity (μ-g) environment that astronauts encounter during spaceflight
can cause severe acute bone loss, the molecular mechanism of this bone loss remains …
can cause severe acute bone loss, the molecular mechanism of this bone loss remains …