Advanced paternal age (APA) is associated with infertility and other reproductive risks.
Studies looking at APA and outcomes have used different paternal age cut‐offs, which has …

Multiple epidemiological studies suggest a relationship between advanced paternal age
(APA) at conception and adverse neurodevelopmental outcomes in offspring, particularly …

Background An explosive increase in couples attending assisted reproductive technology
has been recently observed, despite an overall success rate of about 20%–30 …

Women have been increasingly delaying the start of motherhood in recent decades. The
same trend is seen also for men. The influence of maternal age on fertility, chromosomal …

Purpose Fertility at advanced age has become increasingly common, but the aging of
parents may adversely affect the maturation of gametes and the development of embryos …

Mutation is the ultimate source of all genetic novelty and the cause of heritable genetic
disorders. Mutational burden has been linked to complex disease, including …

BACKGROUND: Advanced paternal age has been linked with an increased risk of
schizophrenia in the offspring. If age-related de novo mutations in the male germ line …

BACKGROUND There is a global tendency for parents to conceive children later in life. The
maternal dimension of the postponement transition has been thoroughly studied, but interest …

Paternal age at conception has been increasing. In this review, we first present the results
from the major mammalian animal models used to establish that increasing paternal age …

Results: It cannot be definitively concluded for or against the neurodevelopmental or
degenerative hypothesis, but efforts in understanding basis of schizophrenia must go on …