Towards an integrated approach for understanding glia in Amyotrophic Lateral Sclerosis

S Majewski, P Klein, S Boillée, BE Clarke, R Patani - Glia, 2024 - Wiley Online Library
Substantial advances in technology are permitting a high resolution understanding of the
salience of glia, and have helped us to transcend decades of predominantly neuron‐centric …

The Current Landscape of Hypotheses Describing the Contribution of CD4+ Heterogeneous Populations to ALS

M Sacharczuk, ME Mickael, N Kubick… - Current Issues in …, 2024 - bazawiedzy.uksw.edu.pl
Amyotrophic Lateral Sclerosis (ALS) is a poorly understood and fatal disease. It has a low
prevalence and a 2–4 year survival period. Various theories and hypotheses relating to its …

Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS

F Limone, DA Mordes, A Couto, BJ Joseph, JM Mitchell… - Nature Aging, 2024 - nature.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by a
progressive loss of motor function linked to degenerating extratelencephalic neurons/Betz …

The gut microbiota is a determinant of sexual dimorphism in ALS-linked TDP43 mice

EJ Beraldi, S Lee, Y Jiang, IM Rea, R Phull… - bioRxiv, 2024 - biorxiv.org
The mechanisms underlying the earlier onset and male predominance of amyotrophic
lateral sclerosis (ALS), the most common form of human motoneuron disease, are poorly …