Rational design of biodegradable thermoplastic polyurethanes for tissue repair

C Xu, Y Hong - Bioactive Materials, 2022 - Elsevier
As a type of elastomeric polymers, non-degradable polyurethanes (PUs) have a long history
of being used in clinics, whereas biodegradable PUs have been developed in recent …

Nerve guidance conduit development for primary treatment of peripheral nerve transection injuries: A commercial perspective

BJ Parker, DI Rhodes, CM O'Brien, AE Rodda… - Acta Biomaterialia, 2021 - Elsevier
Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …

In vitro and in vivo investigation of PLA/PCL scaffold coated with metformin-loaded gelatin nanocarriers in regeneration of critical-sized bone defects

M Shahrezaee, M Salehi, S Keshtkari, A Oryan… - … , Biology and Medicine, 2018 - Elsevier
Large bone defects constitute a major challenge in bone tissue engineering and usually fail
to heal due to the incomplete differentiation of recruited mesenchymal stem cells (MSCs) …

Sophisticated polycaprolactone/gelatin nanofibrous nerve guided conduit containing platelet-rich plasma and citicoline for peripheral nerve regeneration: in vitro and …

H Samadian, A Ehterami, A Sarrafzadeh… - International journal of …, 2020 - Elsevier
Peripheral nerve injury (PNI) is a devastating condition that may result in loss of sensory
function, motor function, or both. In the present study, we construct an electrospun nerve …

Platelet-rich plasma therapy in the treatment of diseases associated with orthopedic injuries

J Fang, X Wang, W Jiang, Y Zhu, Y Hu… - … Engineering Part B …, 2020 - liebertpub.com
Platelet-rich plasma (PRP) is an autologous platelet concentrate prepared from the whole
blood that is activated to release growth factors (GFs) and cytokines and has been shown to …

Porous electrospun poly (ε-caprolactone)/gelatin nanofibrous mat containing cinnamon for wound healing application: In vitro and in vivo study

M Salehi, M Niyakan, A Ehterami… - Biomedical engineering …, 2020 - Springer
In this study, cinnamon (cin) was loaded into poly (ε-caprolactone)/gelatin (PCL/Gel)
nanofibrous matrices in order to fabricate an appropriate mat to improve wound healing …

3D melatonin nerve scaffold reduces oxidative stress and inflammation and increases autophagy in peripheral nerve regeneration

Y Qian, Q Han, X Zhao, J Song, Y Cheng… - Journal of Pineal …, 2018 - Wiley Online Library
Peripheral nerve defect is a common and severe kind of injury in traumatic accidents.
Melatonin can improve peripheral nerve recovery by inhibiting oxidative stress and …

Tissue-Engineered Core–Shell Silk-Fibroin/Poly-l-Lactic Acid Nerve Guidance Conduit Containing Encapsulated Exosomes of Human Endometrial Stem Cells …

MS Namini, S Ebrahimi-Barough, J Ai… - ACS Biomaterials …, 2023 - ACS Publications
Nerve guide conduits (NGCs) have been shown to be less efficient than nerve autografts in
peripheral nerve regeneration. To address this issue, we developed for the first time a novel …

An update–tissue engineered nerve grafts for the repair of peripheral nerve injuries

NP Patel, KA Lyon, JH Huang - Neural regeneration research, 2018 - journals.lww.com
Peripheral nerve injuries (PNI) are caused by a range of etiologies and result in a broad
spectrum of disability. While nerve autografts are the current gold standard for the …

Neural tissue regeneration by a gabapentin-loaded cellulose acetate/gelatin wet-electrospun scaffold

S Farzamfar, M Naseri-Nosar, A Vaez, F Esmaeilpour… - Cellulose, 2018 - Springer
In the present study, gabapentin (GBP), an anticonvulsant drug used as an analgesic to
control the neuropathic pains, was incorporated with cellulose acetate (CA) and gelatin (Gel) …