Cross-domain binding of anti-fibrillation peptide TNGQ to islet amyloid polypeptide provides cytoprotective effects in giant unilamellar vesicles and pancreatic β-cells
Islet amyloid polypeptide (IAPP) fibrillation induces β-cell dysfunction and toxicity in patients
with type 2 diabetes. Cytotoxicity is caused by the ability of IAPP fibrils and fibrillar …
with type 2 diabetes. Cytotoxicity is caused by the ability of IAPP fibrils and fibrillar …
[HTML][HTML] Influence of anti-fibrillation TNGQ peptide and rutin combination on β-cell cytoprotective effects against IAPP-induced cell death and oxidative stress
RO Abioye, OH Adetula, JD Hum… - … and Biophysical Research …, 2024 - Elsevier
Type 2 diabetes development has been associated with islet amyloid polypeptide (IAPP)
fibrillation. IAPP fibrils have various deleterious effects, such as oxidative stress and …
fibrillation. IAPP fibrils have various deleterious effects, such as oxidative stress and …
Functional Significance of Islet Amyloid Polypeptide Anti-fibrillation Compounds as a Novel Treatment for Type 2 Diabetes Management
RO Abioye - 2024 - ruor.uottawa.ca
Amyloidogenic proteins and peptides have been implicated in many diseases including
Alzheimer's, Parkinson's, Huntington's, and even prion disease. Islet amyloid polypeptide …
Alzheimer's, Parkinson's, Huntington's, and even prion disease. Islet amyloid polypeptide …