M2 macrophage-derived exosomes carry microRNA-148a to alleviate myocardial ischemia/reperfusion injury via inhibiting TXNIP and the TLR4/NF-κB/NLRP3 …

Y Dai, S Wang, S Chang, D Ren, S Shali, C Li… - Journal of molecular and …, 2020 - Elsevier
Background Reperfusion may cause injuries to the myocardium in ischemia situation.
Emerging studies suggest that exosomes may serve as key mediators in myocardial …

[HTML][HTML] Mesenchymal stem cell-derived exosomal microRNA-182-5p alleviates myocardial ischemia/reperfusion injury by targeting GSDMD in mice

R Yue, S Lu, Y Luo, J Zeng, H Liang, D Qin… - Cell death …, 2022 - nature.com
Recent evidence indicates that exosomes derived from mesenchymal stem cells (MSCs)
confer protective effects against myocardial ischemia/reperfusion (I/R) injury. Exosomes are …

Tanshinone IIA protects against myocardial ischemia reperfusion injury by activating the PI3K/Akt/mTOR signaling pathway

Q Li, L Shen, Z Wang, HP Jiang, LX Liu - Biomedicine & pharmacotherapy, 2016 - Elsevier
Objective To determine the mechanism by which Tanshinone IIA (Tan IIA) relieves
myocardial ischemia reperfusion injury (MIRI) in rats via the PI3K/Akt/mTOR signaling …

[HTML][HTML] Research progress in cardiotoxicity of organophosphate esters

H Fang, L Yang, M Yan, Y Fan, J Zhu… - Frontiers in Pharmacology, 2023 - frontiersin.org
Organophosphate esters (OPEs) have been extensively utilized worldwide as a substitution
for brominated flame retardants. With an increased awareness of the need for environmental …

Inhibition of miR‐148b ameliorates myocardial ischemia/reperfusion injury via regulation of Wnt/β‐catenin signaling pathway

M Yang, DY Kong, JC Chen - Journal of cellular physiology, 2019 - Wiley Online Library
Our work aims to elucidate the effect how microRNA‐148b (miR‐148b) participated in
myocardial ischemia/reperfusion (I/R) injury via regulation of Wnt/β‐catenin signaling …

[HTML][HTML] Lycium barbarum polysaccharide protects rats and cardiomyocytes against ischemia/reperfusion injury via Nrf2 activation through autophagy inhibition

H Pan, L Niu, Y Wu, L Chen… - Molecular medicine …, 2021 - spandidos-publications.com
The irreversible loss of cardiomyocytes is mainly the result of ischemic/reperfusion (I/R)
myocardial injury, leading to persistent heart dysfunction and heart failure. It has been …

[HTML][HTML] BYD ameliorates oxidative stress-induced myocardial apoptosis in heart failure post-acute myocardial infarction via the P38 MAPK-CRYAB signaling pathway

Y Zhang, C Li, H Meng, D Guo, Q Zhang, W Lu… - Frontiers in …, 2018 - frontiersin.org
Aim: Heart failure (HF) post-acute myocardial infarction (AMI) contributes to increasing
mortality and morbidity worldwide. Baoyuan decoction (BYD) is a well-known traditional …

Propofol‐mediated cardioprotection dependent of microRNA‐451/HMGB1 against myocardial ischemia‐reperfusion injury

Y Li, J Sun, L Hu, X Ma, G Zhou… - Journal of Cellular …, 2019 - Wiley Online Library
Administration of propofol at the time of reperfusion has shown to protect the heart from
ischemia and reperfusion (I/R) injury. The aim of the present study was to investigate the …

[HTML][HTML] Acetyl salicylic acid protected against heat stress damage in chicken myocardial cells and may associate with induced Hsp27 expression

D Wu, J Xu, E Song, S Tang, X Zhang, N Kemper… - Cell Stress and …, 2015 - Elsevier
We investigated whether acetyl salicylic acid (ASA) protects chicken myocardial cells from
heat stress-mediated damage in vivo and whether the induction of Hsp27 expression is …

[HTML][HTML] Tanshinone modulates the expression of Bcl-2 and Bax in cardiomyocytes and has a protective effect in a rat model of myocardial ischemia-reperfusion

R Guo, G Li - Hellenic journal of cardiology, 2018 - Elsevier
Objective To investigate the protective activity of tanshinone in a rat model of myocardial
ischemia-reperfusion and determine its effect on the expression of Bcl-2 and Bax in …