Recent advances in biological production of 3-hydroxypropionic acid

V Kumar, S Ashok, S Park - Biotechnology advances, 2013 - Elsevier
Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced
biologically from glucose or glycerol. This review article provides an overview and the …

Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source

V Kumar, S Park - Biotechnology advances, 2018 - Elsevier
Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol
efficiently under both aerobic and anaerobic conditions. This microbe is considered an …

Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis

XR Jiang, X Yan, LP Yu, XY Liu, GQ Chen - Nature communications, 2021 - nature.com
Hydroxypropionic acid (3HP), an important three carbon (C3) chemical, is designated as
one of the top platform chemicals with an urgent need for improved industrial production …

Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

High Production of 3-Hydroxypropionic Acid in Klebsiella pneumoniae by Systematic Optimization of Glycerol Metabolism

Y Li, X Wang, X Ge, P Tian - Scientific reports, 2016 - nature.com
Hydroxypropionic acid (3-HP) is an important platform chemical proposed by the United
States Department of Energy. 3-HP can be converted to a series of bulk chemicals …

Metabolic engineering of 3‐hydroxypropionic acid biosynthesis in Escherichia coli

HS Chu, YS Kim, CM Lee, JH Lee… - Biotechnology and …, 2015 - Wiley Online Library
Hydroxypropionic acid (3‐HP) can be produced in microorganisms as a versatile platform
chemical. However, owing to the toxicity of the intermediate product 3 …

Recent technological and strategical developments in the biomanufacturing of 1, 3-propanediol from glycerol

E Fokum, HM Zabed, J Yun, G Zhang, X Qi - International Journal of …, 2021 - Springer
In the pursuit of sustainable development, there is a rapid increase in the generation of
biodiesel, which eventually results in the synthesis of glycerol as a major by-product. The …

Extraction, isolation, and purification of value-added chemicals from lignocellulosic biomass

T Chaturvedi, LSS Hulkko, M Fredsgaard… - Processes, 2022 - mdpi.com
This review covers the operating conditions for extracting top value-added chemicals, such
as levulinic acid, lactic acid, succinic acid, vanillic acid, 3-hydroxypropionic acid, xylitol, 2, 5 …

Flux analysis of the Lactobacillus reuteri propanediol-utilization pathway for production of 3-hydroxypropionaldehyde, 3-hydroxypropionic acid and 1,3-propanediol …

T Dishisha, LP Pereyra, SH Pyo, RA Britton… - Microbial cell …, 2014 - Springer
Background Lactobacillus reuteri converts glycerol to 3-hydroxypropionic acid (3HP) and 1,
3-propanediol (1, 3PDO) via 3-hydroxypropionaldehyde (3HPA) as an intermediate using …

Production of 3-hydroxypropanoic acid from glycerol by metabolically engineered bacteria

C Jers, A Kalantari, A Garg, I Mijakovic - Frontiers in Bioengineering …, 2019 - frontiersin.org
3-hydroxypropanoic acid (3-HP) is a valuable platform chemical with a high demand in the
global market. 3-HP can be produced from various renewable resources. It is used as a …