PDX-1: a promising therapeutic target to reverse diabetes

Y Zhang, X Fang, J Wei, R Miao, H Wu, K Ma, J Tian - Biomolecules, 2022 - mdpi.com
The pancreatic duodenum homeobox-1 (PDX-1) is a transcription factor encoded by a Hox-
like homeodomain gene that plays a crucial role in pancreatic development, β-cell …

[HTML][HTML] Exploring the potential of rosemary derived compounds (rosmarinic and carnosic acids) as cancer therapeutics: current knowledge and future perspectives

F Sirajudeen, LJB Malhab, Y Bustanji… - Biomolecules & …, 2024 - ncbi.nlm.nih.gov
Cancer is a global health challenge with high morbidity and mortality rates. However,
conventional cancer treatment methods often have severe side effects and limited success …

Genistin modulates high-mobility group box protein 1 (HMGB1) and nuclear factor kappa-B (NF-κB) in Ehrlich-ascites-carcinoma-bearing mice

MA Saleh, SA Antar, W Abdo, A Ashour… - … Science and Pollution …, 2023 - Springer
Cancer is the world's second-largest cause of death. Although there are numerous cancer
treatment options, they are typically uncomfortable owing to side effects and ineffectual due …

Rosemarinic acid protects β-cell from STZ-induced cell damage via modulating NF-κβ pathway

W El-Huneidi, S Anjum, AK Mohammed, SB Eshaq… - Heliyon, 2023 - cell.com
Rosmarinic acid (RA), a natural ester phenolic compound, is known to have antioxidant and
anti-inflammatory properties. RA has also been reported to exhibit a hypoglycemic effect; …

Diabetes mellitus alters the immuno-expression of neuronal nitric oxide synthase in the rat pancreas

BS Emerald, S Mohsin, C D'souza, A John… - International journal of …, 2022 - mdpi.com
Nitric oxide is generated from nitric oxide synthase following hyperglycemia-induced
oxidative stress during the course of diabetes mellitus (DM). We examined the temporal …

Mechanistic Insights into the Ameliorative Effect of Cichoriin on Diabetic Rats—Assisted with an In Silico Approach

HE Khalil, MF Abdelwahab, HIM Ibrahim, KA AlYahya… - Molecules, 2022 - mdpi.com
Type 2 diabetes mellitus is considered to be a substantial socioeconomic burden worldwide
on both patients and governments. Coumarins are biomolecules with a diversity of biological …

Polyphenols Investigation, Antioxidant and Anticholinesterase Activity of Rosmarinus officinalis L. Species from Southwest Romania Flora

LE Bejenaru, A Biţă, GD Mogoşanu, AE Segneanu… - 2024 - preprints.org
Rosemary is one of the most important medicinal plants for natural therapy due to its multiple
pharmacological properties, such as antioxidant, anti-inflammatory, neuroprotective …

[PDF][PDF] Exploring the Potential of Rosemary Derived Compounds (Rosmarinic and Carnosic Acids) as Cancer Therapeutics: Current Knowledge and Future …

MH Semreen, J Taneera, W El-Huneidi… - 2024 - researchgate.net
Cancer is a global health challenge with high morbidity and mortality rates. However,
conventional cancer treatment methods often have severe side effects and limited success …