Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Microglia and peripheral monocytes contribute to hypersensitivity in rodent models of
neuropathic pain. However, the precise respective function of microglia and peripheral …

Macrophages have been suggested to be beneficial for myocardial wound healing. We
investigated the role of macrophages in myocardial wound healing by inhibition of …

objective. To investigate the role of macrophages in the development of laser-induced
choroidal neovascularization (CNV) by selective depletion with liposomal clodronate (Cl 2 …

OBJECTIVE: In human osteoarthritis (OA), various forms of pathology are observed. Besides
cartilage damage and fibrosis, neogenesis of bone, osteophyte formation, also occurs …

purpose. Macrophage recruitment to the choroid has been proposed to contribute to the
pathogenesis of choroidal neovascularization (CNV) in AMD. The study was conducted to …

BACKGROUND & AIMS: Liver Kupffer cells have been suggested to be heterogeneous
macrophage lineage cells. We explored this possibility by classifying the mouse Kupffer …

Hepatic injury induced by various toxic agents, including acetaminophen (APAP), has been
attributed, in part, to the production of proinflammatory cytokines and other mediators by …

purpose. The role of microglia, present in the retina early in development before
vascularization, remains ill defined. The authors investigated whether microglia are …

Macrophages function as control switches of the immune system, providing a balance
between pro-and anti-inflammatory responses. To accomplish this, they develop into …