Multicomponent reactions for the synthesis of bioactive compounds: A review
CS Graebin, FV Ribeiro, KR Rogério… - Current Organic …, 2019 - ingentaconnect.com
Multicomponent reactions (MCRs) are composed of three or more reagents in which the final
product has all or most of the carbon atoms from its starting materials. These reactions …
product has all or most of the carbon atoms from its starting materials. These reactions …
The Groebke‐Blackburn‐Bienaymé Reaction
A Boltjes, A Dömling - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Imidazo [1, 2‐a] pyridine is a well‐known scaffold in many marketed drugs, such as
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …
Isocyanide-based multicomponent reactions for the synthesis of heterocycles
Multicomponent reactions (MCRs) are extremely popular owing to their facile execution,
high atom-efficiency and the high diversity of products. MCRs can be used to access various …
high atom-efficiency and the high diversity of products. MCRs can be used to access various …
Groebke–Blackburn–Bienaymé multicomponent reaction: emerging chemistry for drug discovery
S Shaaban, BF Abdel-Wahab - Molecular diversity, 2016 - Springer
Abstract The Groebke–Blackburn–Bienaymé reaction (GBBR) is used for the one-pot
synthesis of therapeutically relevant fused imidazoles bridgehead nitrogen heterocyclic …
synthesis of therapeutically relevant fused imidazoles bridgehead nitrogen heterocyclic …
Isocyanide based [4+ 1] cycloaddition reactions: an indispensable tool in multi-component reactions (MCRs)
The advent of cycloaddition reactions in the synthesis of heterocycles and their ever
burgeoning applications in the fields of material chemistry, catalysis and drugs have been a …
burgeoning applications in the fields of material chemistry, catalysis and drugs have been a …
Novel organoselenium-based N-mealanilic acid and its zinc (II) chelate: Catalytic, anticancer, antimicrobial, antioxidant, and computational assessments
S Shaaban, MSS Adam, NM El-Metwaly - Journal of Molecular Liquids, 2022 - Elsevier
Herein we report the synthesis of two novel Zn (II)-complexes (Zn (LgSe) 2 and Zn (Lg) 2)
starting from 4-((4-(methylselanyl) phenyl) amino)-4-oxobut-2-enoic acid (HLgSe) and 4-oxo …
starting from 4-((4-(methylselanyl) phenyl) amino)-4-oxobut-2-enoic acid (HLgSe) and 4-oxo …
Imidazo [1, 2-a] pyridine scaffold as prospective therapeutic agents
Imidazo [1, 2-a] pyridine is one of the most potential bicyclic 5–6 heterocyclic rings that is
recognized as a “drug prejudice” scaffold due to its broad range of applications in medicinal …
recognized as a “drug prejudice” scaffold due to its broad range of applications in medicinal …
Diversity-oriented synthesis of fused-imidazole derivatives via Groebke–Blackburn–Bienayme reaction: a review
In recent time, diversity-oriented synthesis of small chemical entities has been emerged as a
possible tool for exploring the intersections between chemistry and biology. These small …
possible tool for exploring the intersections between chemistry and biology. These small …
Recyclable Perovskite as Heterogeneous Photocatalyst for Aminomethylation of Imidazo‐Fused Heterocycles
T Shi, K Sun, XL Chen, ZX Zhang… - Advanced Synthesis …, 2020 - Wiley Online Library
A sustainable and cost‐effective protocol for direct aminomethylation of imidazo‐fused
heterocycles by decarboxylative coupling reaction of N‐phenylglycines with imidazo‐fused …
heterocycles by decarboxylative coupling reaction of N‐phenylglycines with imidazo‐fused …
Functionalization of imidazo [1, 2-a] pyridines via radical reactions
CH Ma, M Chen, ZW Feng, Y Zhang, J Wang… - New Journal of …, 2021 - pubs.rsc.org
Imidazo [1, 2-a] pyridines are a class of valuable heterocyclic scaffolds in organic synthesis
and pharmaceutical chemistry. The direct functionalization of this valuable scaffold has been …
and pharmaceutical chemistry. The direct functionalization of this valuable scaffold has been …