Cell viability is defined as the number of healthy cells in a sample and proliferation of cells is
a vital indicator for understanding the mechanisms in action of certain genes, proteins and …

Effective treatment of metastatic cancers usually requires the use of toxic chemotherapy. In
most cases, multiple drugs are used, as resistance to single agents occurs almost …

Drug discovery and efficacy in cancer treatments are limited by the inability of pre‐clinical
models to predict successful outcomes in humans. Limitations remain partly due to their lack …

In this review we give an overview of the physiological functions of a group of ATP binding
cassette (ABC) transporter proteins, which were discovered, and still referred to, as …

ATP Binding Cassette (ABC) transporters form a special family of membrane proteins,
characterized by homologous ATP-binding, and large, multispanning transmembrane …

Tumor cells develop resistance to chemotherapeutic drugs through multiple mechanisms.
Overexpression of efflux transporters is an important source of drug resistance. Efflux …

Assessing bacterial contamination in environmental samples is critical in determining threats
to public health. The classical methods are time-consuming and only recognize species that …

The development of high-efficient technologies for cancer biomarkers detection has
attracted tremendous research effort for its great clinic significance. In this work, we …

Abstract MRP1 (ABCC1) is a peculiar member of the ABC transporter superfamily for several
aspects. This protein has an unusually broad substrate specificity and is capable of …

The curability of acute myeloid leukaemia (AML) in a fraction of adult patients was
demonstrated a long time ago. Currently, the probability of cure is consistently above fifty per …