The immunoglobulin (Ig) repertoire achieves functional diversification through several
somatic alterations of the Ig locus. One of these processes, somatic hypermutation (SHM) …

Epigenetics and epigenomic medicine encompass a new science of brain and behavior that
are already providing unique insights into the mechanisms underlying brain development …

There is considerable HIV-1 variation in patients. The extent of the variation is due to the
high rate of viral replication, the high viral load, and the errors made during viral replication …

RNA editing appears to be the major mechanism by which environmental signals overwrite
encoded genetic information to modify gene function and regulation, particularly in the brain …

We review the main lines of evidence (molecular, cellular and whole organism) published
since the 1970s demonstrating Lamarckian Inheritance in animals, plants and …

Accumulating evidence suggests that that non-coding RNAs (ncRNAs) play key roles in
gene regulation and may form the basis of an inter-gene communication system. Many …

Brain serotonin (5-HT) neurotransmission plays a key role in the regulation of mood and has
been implicated in a variety of neuropsychiatric conditions. Tryptophan hydroxylase (TPH) is …

RNA editing is one of the post-transcriptional RNA processes. RNA editing generates RNA
and protein diversity in eukaryotes and results in specific amino acid substitutions, deletions …

The experience of young boys could affect not just their own health in later life, but also the
health of their sons and grandsons. The finding, published in the European Journal of …

A new and diverse range of somatic mutation signatures are observed in late‐stage cancers,
but the underlying reasons are not fully understood. We advance a “combinatorial …