Anti-cancer chalcones: Structural and molecular target perspectives
Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …
Synthesis and pharmacological properties of chalcones: a review
SL Gaonkar, UN Vignesh - Research on chemical intermediates, 2017 - Springer
Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …
research papers have been published, and chalcones continue to show promise for new …
Phyllanthin inhibits MOLT‐4 leukemic cancer cell growth and induces apoptosis through the inhibition of AKT and JNK signaling pathway
H Wang, A Chinnathambi, TA Alahmadi… - … of biochemical and …, 2021 - Wiley Online Library
Among cancers, leukemia is a multistep progression that involves genetic modifications of
normal hematopoietic progenitor cells to cancerous cells. In recent times, leukemia cases …
normal hematopoietic progenitor cells to cancerous cells. In recent times, leukemia cases …
[HTML][HTML] Dietary chalcones with chemopreventive and chemotherapeutic potential
Chalcones are absorbed in the daily diet and appear to be promising cancer
chemopreventive agents. Chalcones represent an important group of the polyphenolic …
chemopreventive agents. Chalcones represent an important group of the polyphenolic …
Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer
In the absence of effective therapy for prostate cancer, there is an immense need for
developing improved therapeutic options for the management of this disease. This study has …
developing improved therapeutic options for the management of this disease. This study has …
Cardamonin: A new player to fight cancer via multiple cancer signaling pathways
Nature's pharmacy has undoubtedly served humans as an affordable and safer health-care
regime for a long times. Cardamonin, a chalconoid present in several plants has been …
regime for a long times. Cardamonin, a chalconoid present in several plants has been …
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
T Eng-Chong, L Yean-Kee, C Chin-Fei… - Evidence‐Based …, 2012 - Wiley Online Library
Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae
family. B. rotunda is widely found in Asian countries where it is commonly used as a food …
family. B. rotunda is widely found in Asian countries where it is commonly used as a food …
[HTML][HTML] Anticancer potential of natural chalcones: in vitro and in vivo evidence
R Michalkova, L Mirossay, M Kello… - International Journal of …, 2023 - mdpi.com
There is no doubt that significant progress has been made in tumor therapy in the past
decades. However, the discovery of new molecules with potential antitumor properties still …
decades. However, the discovery of new molecules with potential antitumor properties still …
Molecular targeted approaches to cancer therapy and prevention using chalcones
DD Jandial, CA Blair, S Zhang, LS Krill… - Current cancer drug …, 2014 - ingentaconnect.com
There is an emerging paradigm shift in oncology that seeks to emphasize molecularly
targeted approaches for cancer prevention and therapy. Chalcones (1, 3-diphenyl-2-propen …
targeted approaches for cancer prevention and therapy. Chalcones (1, 3-diphenyl-2-propen …
[HTML][HTML] Chalcones enhance TRAIL-induced apoptosis in prostate cancer cells
Chalcones exhibit chemopreventive and antitumor effects. Tumor necrosis factor-related
apoptosis-inducing ligand (TRAIL) is a naturally occurring anticancer agent that induces …
apoptosis-inducing ligand (TRAIL) is a naturally occurring anticancer agent that induces …