G-quadruplexes, intricate four-stranded structures composed of G-tetrads formed by four
guanine bases, are prevalent in both DNA and RNA. Notably, these structures play pivotal …

Aging is a prominent risk factor for many neurodegenerative disorders, such as Alzheimer's
disease (AD). Alzheimer's disease is characterized by progressive cognitive decline …

Noncanonical base pairing between four guanines (G) within single-stranded G-rich
sequences leads to formation of а G-quartet. Self-stacking of G-quartets results in a …

G-quadruplexes (G4s) are stable non-canonical secondary structures formed by G-rich DNA
or RNA sequences. They play various regulatory roles in many biological processes. It is …

In cells, the contributions of DEAD-box helicases (DDXs), without which cellular life is
impossible, are of utmost importance. The extremely diverse roles of the nucleolar helicase …

Abstract The protein “BCL-2-associated athanogene-1”(BAG-1), which exists in multiple
isoforms, promotes cancer cell survival and is overexpressed in many different cancers. As a …

Members of the DEAD-box helicase family are involved in all fundamental processes of RNA
metabolism, and as such, their malfunction is associated with various diseases. Currently …

Senecavirus A (SVA), also known as Seneca Valley virus, is a recently discovered
picornavirus that can cause swine vesicular disease, posing a great threat to the global …

DEAD-box RNA helicase 21 (DDX21), also known as RHII/Gu, is an ATP-dependent RNA
helicase. In addition to playing a vital role in regulating cellular RNA splicing, transcription …

The nucleic acid structure called G-quadruplex (G4) is currently discussed to function in
nucleic acid-based mechanisms that influence several cellular processes. They can …