Membrane fusion is a key process in all living organisms that contributes to a variety of
biological processes including viral infection, cell fertilization, as well as intracellular …

Synaptic vesicle recycling is one of the best‐studied cellular pathways. Many of the proteins
involved are known, and their interactions are becoming increasingly clear. However, as for …

In eukaryotes, most intracellular membrane fusion reactions are mediated by the interaction
of SNARE proteins that are present in both fusing membranes. However, the minimal …

Cellular membrane fusion is thought to proceed through intermediates including docking of
apposed lipid bilayers, merging of proximal leaflets to form a hemifusion diaphragm, and …

Membrane fusion is a universal feature of eukaryotic protein trafficking and is mediated by
the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family …

Abstract Synaptobrevin‐2 (Syb2) is a soluble N‐ethylmaleimide‐sensitive factor attachment
protein receptor (SNARE) that is essential for neurotransmitter release. It is the most …

Synaptic vesicles loaded with neurotransmitters fuse with the plasma membrane to release
their content into the extracellular space, thereby allowing neuronal communication. The …

Abstract Synaptotagmin-1 triggers Ca2+-sensitive, rapid neurotransmitter release by
promoting interactions between SNARE proteins on synaptic vesicles and the plasma …

Membrane fusion is fundamental to biological processes as diverse as membrane trafficking
or viral infection. Proteins catalyzing membrane fusion need to overcome energy barriers to …

Rapid neurotransmitter release depends on the ability to arrest the SNAP receptor (SNARE)–
dependent exocytosis pathway at an intermediate “cocked” state, from which fusion can be …