Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present
bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol …

Studies of alterations in histone methylation in cancer have led to the identification of histone
methyltransferases and demethylases as novel targets for therapy. Lysine-specific …

Introduction Multiple myeloma (MM) is a plasma cell neoplasm with substantial morbidity
and mortality. A comprehensive description of the global burden of MM is needed to help …

Background GIP-dependent primary bilateral macronodular adrenal hyperplasia with
Cushing's syndrome is caused by aberrant expression of the GIP receptor in adrenal …

Bone is one of the key components of the musculoskeletal system. Bone and joint disease
are the fourth most widespread disease, in addition to cardiovascular disease, cancer, and …

Primary bilateral macronodular adrenal hyperplasia (PBMAH) is an adrenal cause of
Cushing syndrome. Nowadays, a PBMAH diagnosis is more frequent than previously, as a …

Multiple myeloma (MM) is a hematological malignancy caused by the clonal expansion of
plasma cells. The incidence of MM worldwide is increasing with greater than 140 000 …

Estimating familial cancer risks is clinically important in being able to discriminate between
individuals in the population at differing risk for malignancy. To gain insight into the familial …

Purpose This study aimed to investigate the genetic cause of food-dependent Cushing
syndrome (FDCS) observed in patients with primary bilateral macronodular adrenal …

Simple Summary Multiple myeloma is an incurable blood cancer caused by the malignant
transformation of immunoglobulin-producing plasma cells. The mechanisms leading to the …