[HTML][HTML] Toxicological effects of cadmium on mammalian testis

Q Zhu, X Li, RS Ge - Frontiers in genetics, 2020 - frontiersin.org
Cadmium is a heavy metal, and people are exposed to it through contaminated foods and
smoking. In humans and other mammals, cadmium causes damage to male testis. In this …

Cadmium as a testicular toxicant: A Review

JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …

Effect of heavy metals on epididymal morphology and function: An integrative review

M Machado-Neves - Chemosphere, 2022 - Elsevier
Male fertility has deteriorated over the last decades, and environmental risk factors are
among the possible causes of this phenomenon. Pollutants such as heavy metals might …

Natural antioxidants mitigate heavy metal induced reproductive toxicity: prospective mechanisms and biomarkers

Y Fan, X Jiang, Y Xiao, H Li, J Chen… - Critical Reviews in Food …, 2023 - Taylor & Francis
Heavy metals are harmful environmental pollutants that have attracted widespread attention,
attributed to their health hazards to humans and animals. Due to the non-degradable …

Curcumin protects the testis against cadmium-induced histopathological damages and oxidative stress in mice

HR Momeni, N Eskandari - Human & experimental …, 2020 - journals.sagepub.com
Background: Cadmium is an environmental pollutant which can induce the overproduction
of free radicals while suppressing the antioxidant defense system. Curcumin is considered a …

Subacute testicular toxicity to cadmium exposure intraperitoneally and orally

VGS Mouro, ALP Martins, J Silva… - Oxidative medicine …, 2019 - Wiley Online Library
The toxic effects of cadmium (Cd) on reproductive parameters are widely described in the
literature. Experimental models often make use of the intraperitoneal route (ip), although …

Combined apocynin and carvedilol protect against cadmium-induced testicular damage via modulation of inflammatory response and redox-sensitive pathways

AG Bakr, EHM Hassanein, FEM Ali, EAM El-Shoura - Life Sciences, 2022 - Elsevier
Testicular damage is considered a severe complication of cadmium (Cd) exposure which is
associated with tissue oxidative stress damage, inflammation, and apoptosis. The present …

Cadmium, arsenic, and lead: elements affecting male reproductive health

BT Lovaković - Current Opinion in Toxicology, 2020 - Elsevier
The decline of male fertility has become a serious public health concern over the last
decades, coinciding with an increase in environmental exposure to toxic pollutants. Toxic …

A review on genotoxicity in connection to infertility and cancer

S Choudhuri, T Kaur, S Jain, C Sharma… - Chemico-Biological …, 2021 - Elsevier
Genotoxicity has been identified as the main cause of infertility and a variety of cancers. The
mechanisms affect the structure, quality of the information or the segregation of DNA and are …

[HTML][HTML] Altered expression of DAAM1 and PREP induced by cadmium toxicity is counteracted by melatonin in the rat testis

M Venditti, M Ben Rhouma, MZ Romano, I Messaoudi… - Genes, 2021 - mdpi.com
Cadmium (Cd) is one of the most toxic pollutants for health due to its accumulation in several
tissues, including testis. This report confirms that Cd increased oxidative stress and …