RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Alternative cleavage and polyadenylation (APA) is a widespread mechanism to generate
mRNA isoforms with alternative 3′ untranslated regions (UTRs). The expression of …

Background The four major RNA adenosine modifications, ie, m 6 A, m 1 A, alternative
polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” …

The majority of human mRNAs generate alternative 3′ untranslated regions (UTRs)
through various processes, including RNA modifications such as RNA editing, m 6 A …

Circular RNAs (circRNAs) are a novel class of RNAs, which involve in many physiological
processes and participate in many diseases, especially in cancer. Previous reports showed …

Alternative polyadenylation (APA) is a molecular process that generates diversity at the 3′
end of RNA polymerase II transcripts from over 60% of human genes. APA is derived from …

Simple Summary Circular RNAs (circRNAs) are circular RNA molecules without a 5′ cap
and a 3′ poly (A) tail structure, which play an important role in tumor development, invasion …

Background Alternative polyadenylation (APA) is an important mechanism of gene
expression regulation through generation of RNA isoforms with distinct 3′ termini …

A crucial feature of gene expression involves RNA processing to produce 3′ ends through
a process termed 3′ end cleavage and polyadenylation (CPA). This ensures the nascent …

Alternative polyadenylation (APA) is a gene regulatory process that dictates mRNA 3′-UTR
length, resulting in changes in mRNA stability and localization. APA is frequently disrupted …