Layered double hydroxide-based nanomaterials for biomedical applications
Against the backdrop of increased public health awareness, inorganic nanomaterials have
been widely explored as promising nanoagents for various kinds of biomedical applications …
been widely explored as promising nanoagents for various kinds of biomedical applications …
Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …
Nanocatalytic theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient cancer therapy
Chemodynamic therapy (CDT) is an emerging therapy method that kills cancer cells by
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …
Ablation of gap junction protein improves the efficiency of nanozyme‐mediated catalytic/starvation/mild‐temperature photothermal therapy
Y Li, Y Zhang, Y Dong, OU Akakuru, X Yao… - Advanced …, 2023 - Wiley Online Library
Reactive oxygen species (ROS)‐mediated tumor catalytic therapy is typically hindered by
gap junction proteins that form cell‐to‐cell channels to remove cytotoxic ROS, thereby …
gap junction proteins that form cell‐to‐cell channels to remove cytotoxic ROS, thereby …
Glutathione-depleting nanomedicines for synergistic cancer therapy
X Cheng, HD Xu, HH Ran, G Liang, FG Wu - ACS nano, 2021 - ACS Publications
Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
Recent advances in nanomaterial‐based nanoplatforms for chemodynamic cancer therapy
SL Li, P Jiang, FL Jiang, Y Liu - Advanced Functional Materials, 2021 - Wiley Online Library
Triggered by the endogenous chemical energy in the tumor microenvironment (TME),
chemodynamic therapy (CDT) as an emerging non‐exogenous stimulant therapeutic …
chemodynamic therapy (CDT) as an emerging non‐exogenous stimulant therapeutic …
Strategies for enhancing cancer chemodynamic therapy performance
D Jana, Y Zhao - Exploration, 2022 - Wiley Online Library
Chemodynamic therapy (CDT) has emerged to be a frontrunner amongst reactive oxygen
species‐based cancer treatment modalities. CDT utilizes endogenous H2O2 in tumor …
species‐based cancer treatment modalities. CDT utilizes endogenous H2O2 in tumor …
[HTML][HTML] A tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody
To improve the response rate of immune checkpoint inhibitors such as anti-PD-L1 antibody
in immunosuppressive cancers like triple-negative breast cancer (TNBC), induction of …
in immunosuppressive cancers like triple-negative breast cancer (TNBC), induction of …
[HTML][HTML] Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2, 3-dioxygenase-blockade tumor immunotherapy
L Dai, M Yao, Z Fu, X Li, X Zheng, S Meng… - Nature …, 2022 - nature.com
Inhibited immune response and low levels of delivery restrict starvation cancer therapy
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …