[HTML][HTML] Maternal immune protection against infectious diseases

SN Langel, M Blasi, SR Permar - Cell Host & Microbe, 2022 - cell.com
The maternal immune system protects developing offspring against pathogens before birth
via transplacental transfer and after birth through secreted milk. This transferred maternal …

[HTML][HTML] Nanocarrier vaccine therapeutics for global infectious and chronic diseases

FZ Simnani, D Singh, P Patel, A Choudhury, A Sinha… - Materials Today, 2023 - Elsevier
Immunization has the potential to become a viable weapon for the upcoming pandemic and
save millions of lives, while also dramatically lowering the high mortality rate brought on by a …

Precision adjuvants for pediatric vaccines

A Singh, C Boggiano, DE Yin, L Polakowski… - Science Translational …, 2024 - science.org
Elucidating optimal vaccine adjuvants for harnessing age-specific immune pathways to
enhance magnitude, breadth, and durability of immunogenicity remains a key gap area in …

Characterization and immunogenicity of a novel chimeric hepatitis B core-virus like particles (cVLPs) carrying rotavirus VP8* protein in mice model

T Latifi, S Jalilvand, F Golsaz‐Shirazi, A Arashkia… - Virology, 2023 - Elsevier
Given the efficacy and safety issues of the WHO for approved/prequalified live attenuated
rotavirus (RV) vaccines, studies on alternative non-replicating modals and proper RV …

Effectiveness and impact of monovalent rotavirus vaccination in Afghanistan: a test-negative case–control analysis

P Anwari, E Burnett, N Safi, A Samsor, H Safi… - The Lancet Global …, 2024 - thelancet.com
Background Afghanistan introduced monovalent rotavirus vaccine (Rotarix) into its national
immunisation schedule in January, 2018. While post-licensure studies have shown …

Intermediate levels of pre-existing protective antibody allow priming of protective T cell immunity against influenza

T Ng, V Flores-Malavet, MAM Mansoor… - The Journal of …, 2023 - journals.aai.org
Overcoming interfering impacts of pre-existing immunity to generate universally protective
influenza A virus (IAV)-specific T cell immunity through vaccination is a high priority. In this …

Lactobacillus acidophilus Expressing Murine Rotavirus VP8 and Mucosal Adjuvants Induce Virus-Specific Immune Responses

D Gilfillan, AC Vilander, M Pan, YJ Goh, S O'Flaherty… - Vaccines, 2023 - mdpi.com
Rotavirus diarrhea-associated illness remains a major cause of global death in children
under five, attributable in part to discrepancies in vaccine performance between high-and …

[HTML][HTML] Rotavirus-Specific Maternal Serum Antibodies and Vaccine Responses to RV3-BB Rotavirus Vaccine Administered in a Neonatal or Infant Schedule in …

B Morgan, EA Lyons, A Handley, N Bogdanovic-Sakran… - Viruses, 2024 - mdpi.com
High titres of rotavirus-specific maternal antibodies may contribute to lower rotavirus vaccine
efficacy in low-and middle-income countries (LMICs). RV3-BB vaccine (G3P [6]) is based on …

Co-administration of rotavirus nanospheres VP6 and NSP4 proteins enhanced the anti-NSP4 humoral responses in immunized mice

A Afchangi, S Jalilvand, A Arashkia, T Latifi… - Microbial …, 2022 - Elsevier
Inconveniences associated with the efficacy and safety of the World Health Organization
(WHO) approved/prequalified live attenuated rotavirus (RV) vaccines, sounded for finding …

Rotavirus A infection in pre-and post-vaccine period: Risk factors, genotypes distribution by vaccination status and age of children in Nampula Province, Northern …

A Chissaque, AFL Bauhofer, I Cossa-Moiane, E Sitoe… - PloS one, 2021 - journals.plos.org
Mozambique introduced the monovalent rotavirus vaccine (Rotarix®, GSK Biologicals,
Rixensart, Belgium) in September 2015. Previous analysis, showed that Nampula province …