Boron delivery agents for neutron capture therapy of cancer

RF Barth, P Mi, W Yang - Cancer Communications, 2018 - Springer
Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the
nuclear capture and fission reactions that occur when the stable isotope, boron-10, is …

Boron agents for neutron capture therapy

K Hu, Z Yang, L Zhang, L Xie, L Wang, H Xu… - Coordination Chemistry …, 2020 - Elsevier
Boron neutron capture therapy (BNCT) is a potential cancer radiotherapeutic modality,
which takes advantage of the neutron capture response that occurs when boron (10 B) is …

Boron science

NS Hosmane - New technologies and applications, 2011 - api.taylorfrancis.com
What is boron? The question itself may not seem very significant to many people. Their
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …

Boron chemicals in diagnosis and therapeutics

BC Das, P Thapa, R Karki, C Schinke… - Future medicinal …, 2013 - Taylor & Francis
Advances in the field of boron chemistry have expanded the application of boron from
material use to medicine. Boron-based drugs represent a new class of molecules that …

Convection-enhanced delivery of nanodiamond drug delivery platforms for intracranial tumor treatment

G Xi, E Robinson, B Mania-Farnell, EF Vanin… - … , Biology and Medicine, 2014 - Elsevier
This study examined a novel drug delivery system for treatment of malignant brain gliomas:
DOX complexed with nanodiamonds (ND-Dox), and administered via convection-enhanced …

New boron delivery agents

AG Beck-Sickinger, DP Becker… - Cancer Biotherapy & …, 2023 - liebertpub.com
This proceeding article compiles current research on the development of boron delivery
drugs for boron neutron capture therapy that was presented and discussed at the National …

Evaluation of sodium borocaptate (BSH) and boronophenylalanine (BPA) as boron delivery agents for neutron capture therapy (NCT) of cancer: an update and a …

RF Barth, N Gupta, S Kawabata - Cancer Communications, 2024 - Wiley Online Library
Boron neutron capture therapy (BNCT) is a cancer treatment modality based on the nuclear
capture and fission reactions that occur when boron‐10, a stable isotope, is irradiated with …

Next-generation boron drugs and rational translational studies driving the revival of BNCT

DS Seneviratne, O Saifi, Y Mackeyev, T Malouff… - Cells, 2023 - mdpi.com
BNCT is a high-linear-energy transfer therapy that facilitates tumor-directed radiation
delivery while largely sparing adjacent normal tissues through the biological targeting of …

[HTML][HTML] The role of radiolabeling in BNCT tracers for enhanced dosimetry and treatment planning

S Mushtaq, P Ji, JY Kim, KC Lee, KI Kim - Theranostics, 2023 - ncbi.nlm.nih.gov
Positron emission tomography (PET) and single photon emission computed tomography
(SPECT) are potent technologies for non-invasive imaging of pharmacological and …

In Vivo Application of Carboranes for Boron Neutron Capture Therapy (BNCT): Structure, Formulation and Analytical Methods for Detection

TD Marforio, A Carboni, M Calvaresi - Cancers, 2023 - mdpi.com
Simple Summary Boron neutron capture therapy (BNCT) is an emerging anticancer
treatment. The success of BNCT relies on the delivery of adequate quantities of 10B to tumor …