Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …

Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …

Among the unknowns in decoding the pathogenesis of SARS-CoV-2 persistent symptoms in
Long Covid is whether there is a contributory role of abnormal immunity during acute …

Background The role of adaptive immune responses in long COVID remains poorly
understood, with contrasting hypotheses suggesting either an insufficient antiviral response …

Summary SARS-CoV-2 primary strain-based vaccination exerts a protective effect against
Omicron variants-initiated infection, symptom occurrence, and disease severity in a booster …

Highlights•Human coronaviruses use distinctand similar strategies to counteract innate
defenses.•Insights from SARS-CoV-2 will inspire research on endemic and epidemic …

Recent studies have strengthened the evidence for Epstein–Barr Virus (EBV) as an
important contributing factor in the development of multiple sclerosis (MS). Chronic …

The etiologic mechanisms of post-acute medical morbidities and unexplained symptoms
(Long COVID) following SARS-CoV-2 infection are incompletely understood. There is …

Of those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),~
10% develop the chronic post-viral debilitating condition, long COVID (LC). Although LC is a …

Since the onset of the COVID-19 pandemic, significant progress has been made in
developing effective preventive and therapeutic strategies against severe acute SARS-CoV …