[HTML][HTML] Compendium of current complement therapeutics
WM Zelek, L Xie, BP Morgan, CL Harris - Molecular immunology, 2019 - Elsevier
The complement system is well known for its role in innate immunity and in maintenance of
tissue homeostasis, providing a first line of defence against infection and playing a key role …
tissue homeostasis, providing a first line of defence against infection and playing a key role …
[HTML][HTML] Complementopathies and precision medicine
E Gavriilaki, RA Brodsky - The Journal of clinical …, 2020 - Am Soc Clin Investig
The renaissance of complement diagnostics and therapeutics has introduced precision
medicine into a widened field of complement-mediated diseases. In particular, complement …
medicine into a widened field of complement-mediated diseases. In particular, complement …
Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …
L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …
Guidelines on the use of therapeutic apheresis in clinical practice–evidence‐based approach from the Writing Committee of the American Society for Apheresis: the …
A Padmanabhan, L Connelly‐Smith… - Journal of clinical …, 2019 - Wiley Online Library
ABSTRACT The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating and categorizing …
Special Issue Writing Committee is charged with reviewing, updating and categorizing …
[HTML][HTML] Diseases of complement dysregulation—an overview
EKS Wong, D Kavanagh - Seminars in immunopathology, 2018 - Springer
Atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy (C3G), and paroxysmal
nocturnal hemoglobinuria (PNH) are prototypical disorders of complement dysregulation …
nocturnal hemoglobinuria (PNH) are prototypical disorders of complement dysregulation …
Diagnosis and treatment of thrombotic microangiopathy
GL Thompson, D Kavanagh - International Journal of …, 2022 - Wiley Online Library
Thrombotic microangiopathy (TMA) is characterized by thrombocytopenia, microangiopathic
haemolytic anaemia and end organ damage. TMAs have varying underlying …
haemolytic anaemia and end organ damage. TMAs have varying underlying …
Atypical hemolytic-uremic syndrome: genetic basis, clinical manifestations, and a multidisciplinary approach to management
K Yerigeri, S Kadatane, K Mongan… - Journal of …, 2023 - Taylor & Francis
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy (TMA) defined by the
triad of hemolytic anemia, thrombocytopenia, and acute kidney injury. Microthrombi develop …
triad of hemolytic anemia, thrombocytopenia, and acute kidney injury. Microthrombi develop …
The immunopathology of complement proteins and innate immunity in autoimmune disease
F Defendi, NM Thielens, G Clavarino… - Clinical Reviews in …, 2020 - Springer
The complement is a powerful cascade of the innate immunity and also acts as a bridge
between innate and acquired immune defence. Complement activation can occur via three …
between innate and acquired immune defence. Complement activation can occur via three …
[HTML][HTML] The glomerulus according to the mesangium
K Ebefors, L Bergwall, J Nyström - Frontiers in Medicine, 2022 - frontiersin.org
The glomerulus is the functional unit for filtration of blood and formation of primary urine.
This intricate structure is composed of the endothelium with its glycocalyx facing the blood …
This intricate structure is composed of the endothelium with its glycocalyx facing the blood …
Extra-renal manifestations of atypical hemolytic uremic syndrome
C Formeck, A Swiatecka-Urban - Pediatric Nephrology, 2019 - Springer
Atypical hemolytic uremic syndrome (aHUS) is a rare and complex disease resulting from
abnormal alternative complement activation with a wide range of clinical presentations …
abnormal alternative complement activation with a wide range of clinical presentations …