Abstract Background Quality by Design (QbD) is a pharmaceutical quality management
system that predicts, controls, and systematically responds to risks that may occur in the …

The successful development of nonviral delivery systems for nucleic acids has been
reported extensively over the past years. Increasingly employed to improve the delivery …

The objective of the current study was to develop an optimized formulation for orally
disintegrating tablets (ODTs) containing melatonin. Different particle sizes of mannitol (ie …

In this study, within the framework of Quality by Design which is a systematically scientific
approach which enables to understand and control the production and formulation variables …

This book offers a comprehensive exploration of the Quality by Design (QbD) methodology,
guiding readers from theory to practical application with accessible examples. It equips …

Emulgel is considered as emulsions, either oil-in-water or water-in-oil type, that is formed via
blending with a gelling agent. Their common usage as pharmaceutical dosage form results …

The legislations have almost frozen the processes used in pharmaceutical manufacturing
overtime. Even after the receipt of drugs' permits/certificates, even a small change in the …

Although the first application of Quality by Design (QbD) concept started for product
development studies, the number of studies regarding its application to analytical …

Critical scientific, technological, and regulatory constraints in pharmaceuticals' study,
development, and marketing must be addressed using a more comprehensive, systematic …

Juran introduced the concept of quality by design (QbD) initially, who held view that quality
ought to be scheduled and believed that the majority of quality crises and issues stem form …