Antioxidative and anti-inflammatory activity of ascorbic acid

A Gęgotek, E Skrzydlewska - Antioxidants, 2022 - mdpi.com
Ascorbic acid, as a one of the basic exogenous vitamins, occurs in the body in the form of
ascorbate, known for its strong antioxidant and anti-inflammatory properties. The presented …

High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer

F Böttger, A Vallés-Martí, L Cahn… - Journal of experimental & …, 2021 - Springer
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer
agent when administered intravenously and in high doses (high-dose IVC). Early phase …

Novel strategies to reverse chemoresistance in colorectal cancer

SC Ma, JQ Zhang, TH Yan, MX Miao, YM Cao… - Cancer …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is a common gastrointestinal malignancy with high morbidity and
fatality. Chemotherapy, as traditional therapy for CRC, has exerted well antitumor effect and …

[HTML][HTML] New oral and topical approaches for the treatment of melasma

PE Grimes, S Ijaz, R Nashawati, D Kwak - International journal of women's …, 2019 - Elsevier
Melasma is a common, therapeutically challenging, and universally relapsing disorder of
hyperpigmentation that is most often observed in women and individuals with Fitzpatrick …

[HTML][HTML] The potential role of vitamin C in empowering cancer immunotherapy

T Bedhiafi, VP Inchakalody, Q Fernandes… - Biomedicine & …, 2022 - Elsevier
Vitamin C also known as L-ascorbic acid is a nutrient naturally occurring in many fruits and
vegetables and widely known for its potent antioxidant activity. Several studies have …

An overview of the antioxidant effects of ascorbic acid and alpha lipoic acid (in liposomal forms) as adjuvant in cancer treatment

M Attia, EA Essa, RM Zaki, AA Elkordy - Antioxidants, 2020 - mdpi.com
Antioxidants are known to minimize oxidative stress by interacting with free radicals
produced as a result of cell aerobic reactions. Oxidative stress has long been linked to many …

PEGylated chitosan nanoparticles encapsulating ascorbic acid and oxaliplatin exhibit dramatic apoptotic effects against breast cancer cells

SA Fahmy, A Ramzy, AA Mandour, S Nasr… - Pharmaceutics, 2022 - mdpi.com
This study aims to design a pH-responsive dual-loaded nanosystem based on PEGylated
chitosan nanoparticles loaded with ascorbic acid (AA) and oxaliplatin (OX) for the effective …

Vitamin C as a Modulator of the Response to Cancer Therapy

W Blaszczak, W Barczak, J Masternak, P Kopczyński… - Molecules, 2019 - mdpi.com
Ascorbic acid (vitamin C) has been gaining attention as a potential treatment for human
malignancies. Various experimental studies have shown the ability of pharmacological …

Ascorbic acid-loaded gliadin nanoparticles as a novel nutraceutical formulation

S Voci, A Gagliardi, M Fresta, D Cosco - Food Research International, 2022 - Elsevier
Ascorbic acid (AA) is one of the foremost antioxidants. Unfortunately, its sensitivity to
different external stimuli such as light, heat and oxygen are concrete limitations for its use …

Ascorbate as a bioactive compound in cancer therapy: the old classic strikes Back

J González-Montero, S Chichiarelli, M Eufemi, F Altieri… - Molecules, 2022 - mdpi.com
Cancer is a disease of high mortality, and its prevalence has increased steadily in the last
few years. However, during the last decade, the development of modern chemotherapy …